Drug Interactions

Drug Interactions

Adverse drug interactions happen with alarming frequency. By some estimates, up to a third of hospital admissions are caused by adverse drug interactions. And adverse drug interactions are also a frequent cause of non-response to treatment.

This lecture covers the basics of drug metabolism and highlights several important psychiatric drug-drug interactions that patients as well as prescribers should be aware of.

SZconsult is a free consultation + education service offered by Northeast Ohio Medical University. It's open to any clinician who wants to learn more about schizophrenia-spectrum illness, or who wants to tap into the collective wisdom of the learning community to find answers to clinical problems.

⌛ Video Chapters ⌛
00:00 - Drug Interactions
00:11 - Objectives
00:36 - Why focus on Drug Interactions
02:28 - Definitions
03:10 - Pharmacodynamic Considerations
08:03 - Pharmacokinetic Considerations
10:11 - CYP enzyme family
11:07 - Enzyme Inducers
14:48 - Enzyme Inhibitor
17:37 - Glucoronidation inhibitor
19:15 - Patient Focused Approach
19:58 - Substrate Consideration
20:53 - Summary

Drug Interactions
Ask A Psychiatrist