END OF TIRZEPATIDE COMPOUNDING? FDA Removes Zepbound and Mounjaro from Shortage List!

The FDA removes Zepbound and Mounjaro from drug shortage list. Is this the end of compounded tirzepatide?

[alphatango]

I called to refill my prescription today at my compounding pharmacy. I was informed of this change. I lost over 100 lbs on this medication and it saved my life. Very frustrating

[raffinataonline]

And other countries pay less than $100. The US is truly the cash cow for these companies.

[lmktacwa]

Yup, have a 7.5mg Zepbound Rx but my pharmacy is out of stock. Seems like that would be a good case for allowing compound Tirzepatide as a substitute, then try to fill the Zepbound again next month. Obviously Eli Lilly is not being completely truthful about availability, and shame on the FDA for cowtowing. 😖

[stevehofer]

The US government needs to buy out the patent under eminent domain to serve the public health.

[staceycooper]

Great video, and easy to understand! Thank you I hope the government will step in, I was using compound pharmacy because my insurance won't cover these drugs for weight loss and I couldn't afford $1500 a month. I cried, I have hypothyroidism and for 20 years with exercise and starvation haven't been able to loose weight before taking this drug. I hope more physicians like your self advocate for change otherwise millions of americans will suffer. Obesity is a disease not a choice.

[grahampearce]

I do not understand why Americans are paying circa $1, 000 dollars for a US manufactured drug (Eli Lilly) when in the UK it sells for circa £200 ($261).

Are the manufacturers taking the proverbial, or is the local supply chain just ripping off customers.

[teresahawkins]

My pharmacy done b12 with it, and They said they can continue

[PurePharmas-qmbk]

We sell only to research facilities. Was wondering why so many trying to order. Just adding B6 or B12 will not work with the FDA. We are looking into adding 3 or 4 peptides in small, beneficial amounts to overcome this issue

[randomupdates]

Update: I was able to stay on tirzepatide compound. Oct 11th the FDA decided to revisit decision, and allowing refills. At least 2-3 months and possibly longer is what my provider said.

[gablovesplantssydney]

If you read the FDA rules, they state that you need to change one of the base ingredients in order to have it be a significant change to the drug. This means that adding something like B6 is not acceptable under their rules.

The reason for this is that it would be quite simple for a patient to take the drug and then take a shot of B6 or a pill of B6 separately to get the same effect.

If you had a patient who was allergic to a preservative they put in the base ingredient and the compounders made the drug up without that ingredient then that would be a reason to be able to produce a compounded version. It also seems that if a doctor is continually writing that all of their patients are allergic to a preservative or to one particular component in the brand-name medication that will not be looked upon favorably so I don’t think that that would work as an excuse long-term to produce a lot of of compounded medication.


You are correct that it doesn’t get around the patent infringement problem.

You can look up the FDA website and read the instructions around the rules. It’s quite clear.

[LawsLady]

They shouldn’t charge this much for medication,

[PatriciaSolismua]

It’s disheartening that these medications have helped so many Americans improve their health—reducing high blood pressure, eliminating diabetes, and transitioning from frequent doctor visits to just an annual physical—only for many insurance companies to now refuse coverage. It feels like they prioritize keeping people dependent on multiple medications and frequent doctor visits over promoting true health. This situation is deeply unfair and shouldn’t be allowed.

[terrigalvin]

My compounding pharmacy adds niacin. How do you patent a peptide that is already in your body? Get ready for the court battles.

[randomupdates]

I had just started the compound, 2 shots in. Already lost 6 pounds. Irritating. Can’t afford like triple for actual zepbound. Going to complete the 4 weeks, but guess I’ll have to switch to semaglutide.

[silverpleiades]

I can't even find a doctor in NYC that will prescribe compounded medicine, let alone compounded tirzepatide. I don't want to use a third party company that will add their monthly fees to an already expensive compounded drug. Any advice?

[jonathanzivan]

Do you have any recommendations for folks that would like to titrate off Mounjaro ? I’ve been on 15mg for 25 months. Huge success. But I’d like to safely get off without gaining my 80lbs back. Mainly I want to keep muscle mass, which can be a problem?

[liisabjork]

I received my forst trizepitide compund today. No problem here.

[lafsatx]

How will this affect those who couldn’t get the name brand due to their medical plan, such as non diabetic medicaid recipients?

[nowwhat]

I would have thought all this would be resolved now. What a disaster.

[kaseysmith]

Trizeptide is still available through online compounding pharmacies. Not sure where you're getting your info. I'm on the compounded trizeptide.