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Chapter 21 Part 2 Innate Immunity Inflammation Fever
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This video was recorded in 2021 for Anatomy & Physiology 2 students at the Community College of Allegheny County - Allegheny Campus.
Topics include:
IMMUNITY
Figure 20.1 Overview of innate and adaptive defenses. Marieb, Pearson textbook
Barriers to Entry
Cells & Chemicals of Innate Immunity
Macrophages
Neutrophils
Natural Killer (NK) Cells
Cytokines
Interferons
Complement System
Inflammation
Inflammatory Response
Inflammatory Response: Edema
Fever
00:00:00 The video discusses the different lines of defense that the immune system has, including the barrier defenses and the innate immune response. It also discusses inflammation and fever, and explains how coronavirus proteins create antigens that the body can generate an immune response against.
00:05:00 The skin is the largest organ of the body and is the most important organ when it comes to acting as a line of defense. The skin has cells that act as a barrier and it has keratinized cells that make it difficult for things to latch onto the skin. The skin also has langerhan cells that are like macrophages and they are associated with the skin.
00:10:00 The video discusses the role of the immune system, including the innate immunity and the adaptive immunity. It explains how the innate immunity protects the body from pathogens and how the adaptive immunity helps the body to recognize and destroy pathogens. It also discusses how the good normal flora helps to protect the body against infections. Finally, the video discusses the importance of washing hands and mouth, and discusses how prebiotics can help to increase the number of good bacteria in the body.
00:15:00 The video discusses the various cells that participate in the innate immune response, and how the adaptive immune system is also involved. It explains that the route of entry for vaccines is usually through the adaptive immune system, which bypasses some of the barriers in the innate immune response.
00:20:00 This video covers the basics of innate immunity, including the role of phagocytic cells (macrophages), cytokines, and complement proteins. It also discusses the benefits of fasting, which can help break down worn out cells.
00:25:00 This video discusses how macrophages help to fight off pathogens by releasing lysosomal enzymes, defensins, and free radicals. It also explains how neutrophils differ from macrophages and how neutrophils play a role in the immune system.
00:30:00 The immune system functions by secreting cytokines and chemokines that help cells communicate and prevent viral or bacterial replication. Cytokines and chemokines are also responsible for the body's inflammatory response. When an individual gets injured or suffers from an infection, their immune system responds by secreting cytokines and chemokines. These cytokines and chemokines activate other cells, which then help the individual heal.
00:35:00 The complement system helps to destroy pathogens by stimulating phagocytosis and oxidation. It also enhances the effects of inflammation, triggers phagocytosis and oxidation, and stimulates an immune response.
00:40:00 The video discusses the purpose of inflammation, which is to help prevent the spread of pathogens, dilute the pathogens, remove debris, and promote tissue repair. It also discusses the five cardinal signs of inflammation: redness, swelling, heat, pain, and impairment of function. Vasodilation is important in the inflammatory response, and pain and loss of function can occur as a result of inflammation.
00:45:00 This video discusses the role of fever in the body and its various functions. It explains that fever is a normal response to injury or illness, and that it can help to stimulate the immune system. It also points out that there are some circumstances in which fever can be considered abnormal.
00:50:00 This video discusses how the body's temperature is raised in order to fight off an infection. The body then goes through various processes to keep the temperature high, such as increased respiration and vasodilation. Once the temperature reaches a certain point, the body stops getting the response from the inflammatory cells, indicating that the infection has been defeated.
Topics include:
IMMUNITY
Figure 20.1 Overview of innate and adaptive defenses. Marieb, Pearson textbook
Barriers to Entry
Cells & Chemicals of Innate Immunity
Macrophages
Neutrophils
Natural Killer (NK) Cells
Cytokines
Interferons
Complement System
Inflammation
Inflammatory Response
Inflammatory Response: Edema
Fever
00:00:00 The video discusses the different lines of defense that the immune system has, including the barrier defenses and the innate immune response. It also discusses inflammation and fever, and explains how coronavirus proteins create antigens that the body can generate an immune response against.
00:05:00 The skin is the largest organ of the body and is the most important organ when it comes to acting as a line of defense. The skin has cells that act as a barrier and it has keratinized cells that make it difficult for things to latch onto the skin. The skin also has langerhan cells that are like macrophages and they are associated with the skin.
00:10:00 The video discusses the role of the immune system, including the innate immunity and the adaptive immunity. It explains how the innate immunity protects the body from pathogens and how the adaptive immunity helps the body to recognize and destroy pathogens. It also discusses how the good normal flora helps to protect the body against infections. Finally, the video discusses the importance of washing hands and mouth, and discusses how prebiotics can help to increase the number of good bacteria in the body.
00:15:00 The video discusses the various cells that participate in the innate immune response, and how the adaptive immune system is also involved. It explains that the route of entry for vaccines is usually through the adaptive immune system, which bypasses some of the barriers in the innate immune response.
00:20:00 This video covers the basics of innate immunity, including the role of phagocytic cells (macrophages), cytokines, and complement proteins. It also discusses the benefits of fasting, which can help break down worn out cells.
00:25:00 This video discusses how macrophages help to fight off pathogens by releasing lysosomal enzymes, defensins, and free radicals. It also explains how neutrophils differ from macrophages and how neutrophils play a role in the immune system.
00:30:00 The immune system functions by secreting cytokines and chemokines that help cells communicate and prevent viral or bacterial replication. Cytokines and chemokines are also responsible for the body's inflammatory response. When an individual gets injured or suffers from an infection, their immune system responds by secreting cytokines and chemokines. These cytokines and chemokines activate other cells, which then help the individual heal.
00:35:00 The complement system helps to destroy pathogens by stimulating phagocytosis and oxidation. It also enhances the effects of inflammation, triggers phagocytosis and oxidation, and stimulates an immune response.
00:40:00 The video discusses the purpose of inflammation, which is to help prevent the spread of pathogens, dilute the pathogens, remove debris, and promote tissue repair. It also discusses the five cardinal signs of inflammation: redness, swelling, heat, pain, and impairment of function. Vasodilation is important in the inflammatory response, and pain and loss of function can occur as a result of inflammation.
00:45:00 This video discusses the role of fever in the body and its various functions. It explains that fever is a normal response to injury or illness, and that it can help to stimulate the immune system. It also points out that there are some circumstances in which fever can be considered abnormal.
00:50:00 This video discusses how the body's temperature is raised in order to fight off an infection. The body then goes through various processes to keep the temperature high, such as increased respiration and vasodilation. Once the temperature reaches a certain point, the body stops getting the response from the inflammatory cells, indicating that the infection has been defeated.
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