Rare Interview with Nobel Prize Winner, Dr. Yoshinori Ohsumi on Autophagy

On a recent trip to Japan, I was fortunate enough to have met and interviewed some very interesting individuals, each of whom will be highlighted in upcoming videos. I spoke to an award-winning scientist on his studies on the incredible effects of hydrogen on the human body, as well as visiting a hydrogen spa and partaking in their hydrogen facial! I also met a beauty expert who imparted so much fascinating knowledge that us westerners simply aren’t aware of that contribute toward their amazing youthful appearance and glowing skin. And in my spare time I simply soaked in the amazing culture, which, as a wellness explorer, and being ever curious, allowed me a glimpse into Japan’s goldmine of fascinating information with regards to health, nutrition, and longevity. I had a camera in tow, so expect to see a lot of content coming soon!
 
However, of all the wonderful and insightful experiences I had during my trip, none were quite as overwhelming and memorable as my interview with the renowned, Nobel prize-winning (2016) scientist, Dr. Yoshinori Ohsumi, an expert on autophagy, for which his studies and findings won him many awards worldwide, as well as the coveted Nobel Prize, and shed light on new areas of fasting and autophagy. 
 
Autophagy is a word which many of you have heard but for those of you who are unfamiliar with it, it literally translates as self-eating, coming from the Greek words: auto — self, and phagy — to eat. You may have heard me mention the word while talking about fasting, a subject that fascinates me endlessly, and of which I am a strong proponent. In fact, my first book, Glow15, was written on the subject. However, do not fear, self-eating doesn’t mean cannibalization! It is a miraculous a natural process in the body whereby our bodies will literally eat our toxic cells, resulting in cellular recycling, which can, among many other things, help prevent chronic illness. It is also a complete body detox and of course works against the aging process by “eating” or degrading damaged organelles, cell membranes and proteins. When autophagy slows or does not function properly, it is thought to be one of the main reasons for the accumulation of damaged cells and aging. It is a science that does not cease to amaze me. And, as Dr. Ohsumi says himself: in his 30 years of study on the subject and to date, we only understand about 30% of the science and miracle of autophagy.
 
Being a very private and introverted individual, I was deeply honored to have been granted access to Dr. Ohsumi’s laboratory at the Tokyo Institute of Technology, and to sit and chat with him about his studies. This rare opportunity was truly an honor and one of his first filmed interviews since winning the Nobel prize in 2016. Dr. Ohsumi is a gentleman, and the epitome of Japanese politeness and humility, as well as being a very soft spoken, modest individual.
 
I hope the information in this video inspires you to learn more on the subject of fasting and autophagy. It is an area we will be devoting a lot of time to and exploring within this channel, so if you haven’t already, be sure to subscribe to receive notifications on upcoming videos. I would also encourage you to check out some of our other existing videos on fasting. To learn more about Dr. Ohsumi himself and his work, you can visit the following links. 

As always, thank you for watching and I hope you enjoy this video. Please be sure to post any questions or comments below.
To your health and happiness :)
-Naomi

[kulsuma]

I started autophagy and started eating healthy 3 months ago. Now I am no longer diabetic, no high blood pressure, and cancer-free. Also, lost weight (A total plus). My skin improved tremendously

[karenalmeria]

Dr. Ohsumi, a lot of people in the world now benefits good health freely because of your 30yrs study of Autophagy. Thank you very much sir. God bless you more!

[desertshield]

He's a humble genius and represents the best part of what it means to be a human. That's what I have to say about Mr. Ohsumi.

[ncbluegrassevents]

Yes, born 1945 world war ii was over. In japan really hard time to get food. Mom got TB and she stayed in bed for a long time - really hard time to get enough food. That time all people were poor in Japan. Everyone overcome those problems.

Yes, i know about Noble prize. I was not so healthy boy, dream was to become a scientist. My father was working at the University. Not so far from University. I wanted to be a scientist.

One point, I didn’t want to be in a competitive field. When i started in vacole not many people were working on that subject. That was very good for me. I wasn’t confident and not many people were working in that field. I might not do it now as many people are working on autophagy.

Okay, for me i want to understand how cell is dynamic. Actually life is adjustable not so many people interested in degradation. lots of people work on ... not so many on the degradation. Degradation is important. The function of the degradation process. For me, degradation must be equally important. Function of the degradation process. Almost every function of the body has degradation . Important for me autophagy so important for the cell. We only know 30% understanding of autophagy and been working on it 30 years. Autophagy is not so long history. That’s my feeling on autophagy

I always showed the slide how the body makes 200 grams protein a day. But we take 70-80 grams from food. Two figures tells us that new protein comes .... important to understand.

So ya, for me surprising fact all protein is replaced every two or 3 months. All protein in body replaced. Life is maintained.

These days, many many casts or company or newspapers sold many people ... already 3-4 years situation happen for me. So noisy.

Hard to say, several people say you will have this in 2-3 years. I not think about that.

Took 3 years to publish paper. I wanted to publish 2 papers but not a good way. Took a long time for me. Something new, take that long.

Probably as i said autophagy so basic a function of the cell to understand the cell or our body. Autophagy must be involved in many things. Autophagy is involved in so mnay things. Reason my work autophagy in yeast cells.... dissect yeast .... most important cell first genes. Understand autophagy. Autophagy genes in plants and showed ...
not so easy to analyze... still difficult... ag genes... research you can analyze autophagy by ag genes. Completely changed research all over the world. Everyone started studying autophagy. Finding the discovery of the ag genes most important.

Sorry. Hum. Still okay. Many people interested in autophagy for disease and health problems. I think it is quite reasonable. Degredation is important. Cells should be maintained clean. Very important for our cells. Autophagy one function is recycle cell... eliminates harmful material in the cell. Those kind must be very important to cells and diseases. Still don’t have special medicine to regulate autophagy but might be New science.

Probably not familiar.

Hum. Okay. For me, so hum. What should I say. Yeah, of course we have many serious problems. Each people have their own serious problems... important... learn a lot how our body working . How whole body is organized. Yeast cell is simple one cell. Still we have many problems to solve. Every cell has a different function. Important to know how cell communication with each other. Every cell has its autophagy function. Own cell autophagy might be the problem. How different cells have different function. Important....some simple... autophagy might not help some people’s health. We need more work on autophagy how it’s regulation in every cell in our body.

Okay. I am already quite old. I don’t know how long i will continue my work. I want to have a really good measuring.... what is degradation and how much extent autophagy does in that cell. I want to have biochemistry to just use yeast cell. Improve our knowledge of how it works in Our body

missed a little but maybe it will help you understand better what he is saying discovered at least 15 genes involved with controlling autophagy in the yeast cell.

[azilakomar]

He is in his 70s and yet he looks young and mentally alert. His skin has a glow of a young person. That is so awesome!

[susansauls]

I watched this twice, second time with closed captioning, which was a huge help. This was a very important interview from a great man, and I wanted to understand and soak in everything he said.
His quote at the end says it all about him and his accomplishments, something we can all learn from if we want to achieve any level of greatness in our lives. After achieving the highest honor in his field, this is his response, that all that has done was to open so many more questions. Words to live by. What an incredible man. For his achievements he is very humble because his focus is on his work, not himself. This was much more than an interview on the authority on autophagy. This was what greatness truly is, something we can all learn from. Thank you so very much for this interview and video.

[cosaovidiu]

Such a beautiful position he takes throughout the interview, that of a Nobel prize winner but always open to learn and have his position from studies and papers challenged. What a truly humble and a beautiful human being and a scientist is Mr. Yoshinori Ohsumi ❤️

[Gaia.S]

Kind of wish the interview was in his native language and we had subtitles so he could articulate what he is saying better.

[manjuvermamadan]

It's a privilege to listen to him in one to one. He is a great achiever still humble. Thanx for organising it....

[saitabla]

The greatest amongst us are the most humble.🙏

[happy__share]

Woooow Naomi! I am so grateful for this interview! It was really touching how this inspiring person keeps researching and explaining with so much humbleness! You did a very good job giving him the time to find the right words to express himself. So precious and so respectful! You are a very special person, Naomi! Many many blessings to you and your loved ones from Germany 🩵🩵🩵🩵🩵🩵🩵

[joylopez]

Dr. Yoshinori Ohsumi rocks!
Love, love his contributions to the body of human

[danmauney]

Learning about ketones and autophagy just recently has totally changed my health. I am inspired by his work and I thank him and you for presenting him to me! Thanks, Naomi!

[CathyPinAZ]

What an honor to hear Dr. Ohsumi speak about his life’s work and what drove his research! So gracious and thoughtful in his answers. Thank you Naomi! ❤️

[sylviabutler]

what a gracious gentleman. He answered your well thought out questions in ways we could all understand. The most important thing I took out of this, is not to worry about fasting destroying our muscles, as our body will make the protein it needs to maintain them through Autophagy by using up all those degrading cells!

[deborahnarendorf]

What an amazing man! His dedication to this complicated area of cell life and its impact is somewhat mind boggling.
Like he said his work over these many years has uncovered a small part of understanding the degradation process,
and now so many more questions have arisen. He is so humble. I loved watching him formulate his answers.
What an amazing mind! Thank you so much for sharing this interview.

[lukelaoh]

Thank you dr Yoshi ....
We were blessed so much.

[dollycrocker]

What a gentle man. He is a great thinker and genius. Humble and kind.

[crystaltilley]

So refreshing to see such a humble genius who is worthy of praise. You can see he dont feel he deserves all this attention he dont seem to want it. Which is so amazing bc so many who have no talent no brains recieve so much attention and they eat it to right up and are the opposite not humble.

[rochelisa]

It was awesome to listen Autophagy from its discoverer. Good luck to him in his future work. I have so much respect for him 🙏