Supplements Shown to Extend Lifespan - Top Longevity Program Results

Timestamps
00:40 ITP overview
01:39 Acarbose
04:46 Canagliflozin
05:29 Aspirin
07:32 Glycine
09:57 Captopril
10:54 NDGA
11:20 Protandim
12:20 Rapamycin
15:00 17-alpha-estradiol
16:40 Compounds that didn't increase lifespan

Disclaimer
I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only.

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Follow me on social media:

[Aaron-iuhg]

What I appreciate about Siim's methods is the simplicity and just how few supplements he is taking compared to other longevity influencers.

[markusantonious]

What is always left out of these discussions are the synergistic effects of multi-supplement formulations. My good friend and now Prof. Emeritus, C.D. Rollo of McMaster University, Hamilton, Ont., performed over a decade of aging experiments on mice and rats starting in the early 2000s in which a supplement stack of some 40 or so nutrients - many of them just simple vitamins, B complex, garlic, etc. along with NAC, alpha lipoic acid, acetyl L carnitine - not only extended maximal lifespan by 10%, but even more significantly, *completely abolished* cognitive decline in these animals. This notion of multi-stack supplementation follows the original protocols of Denham Harman, the godfather of the 'free radical theory of aging' who also emphasized the synergistic and interdependent nature of supplementation. Focusing on single supplements is, essentially, largely missing the boat here.

[Bocajbocaj-ddht]

I bought your book "Longevity Leap" and it's very much worth it. I enjoy your writing style.

[rainfun]

i learnt about glycine and started taking it 2 months ago because of your videos.... thank you 🎉

[yuvalkapellner]

The main reason for aspirin prescription is its mild blood thinning effect which have benefited heart patients. However it is just better to take quercetin at the right dosage as it is a blood thinner as well and also works to attenuate cd38 and anti inflammatory as well as anti histamine. But pharma wants to sell their stuff.

[TomHimanen]

Does TMG (trimethyl-glycine) have equal longevity benefits as regular glycine? I take TMG because it is a methyl donor and good for methylation and longevity, and after losing methyl molecules TMG is left with glycine. So I think it is enough and even better to eat TMG without needing to take glycine separately on top of it.

[leonsamsworth]

Any plans for an Audible release of the new book?
Thanks for all the content by the way.

[unjaded]

always with all the correct info and simple precise explanation. aciu Siim

[IanRushtonMusic]

Surprised Taurine wasn't on the list

[dikshaedythe]

Awesome presentation. Can save people a lot of time and money.

[haidersyed]

I take 2000mg TMG and 1200mg NAC daily and I feel amazing

[jozefwoo]

Thanks, nice overview. What brand of glycine do you take? And wasn't GlyNac also tested by the ITP?

[HvdHaghen]

Why are Astaxanthin and meclizine not mentioned? They are tested in the ITP program and extended lifespan in male mice (2019).

[niellalien]

Hi, Siim. I really appreciate your vids!!! I have a question -- if we take NAC every day, do we need to supplement with trace minerals and B-complex every day?

[david-jrfn]

curcumin extended lifespan by as much as 25% but C60 had the biggest effect of 90% extension

[crazyinvestoor]

What do you think about Ergothioneine?

[FXDUBOIS]

Aspirin is also a light mTOR inhibitor! For the rest, big 👍👍👍

[Therandeon]

Does taking Magnesium Glycinate give you some glycine as well?

[thomasyoung]

Does magnesium glycinate have the same form of glycine as TMG?trimethylglycine).

[jusufagil]

Do you recommend for the elderly who also don't do any resistance training to take creatine or is creatine only best taken by those who are doing resistance training?