Venous Thromboembolism (DVT, PE) | Clinical Medicine

Ninja Nerds!
Professor Zach Murphy will present on Venous Thromboembolism, including Pulmonary Embolism (PE) and Deep Vein Thrombosis (DVT). We will be going into detail on the following main objectives:

1. Definition and Classification of Venous Thromboembolism
- Acquire an in-depth understanding of Venous Thromboembolism, a condition involving the formation of blood clots in the venous system.
- Explore the two main types of VTE: Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).

2. Pathophysiology and Etiologies
- Uncover the underlying mechanisms leading to VTE, focusing on the triad of stasis, hypercoagulability, and endothelial injury.
- Investigate common risk factors such as surgery, malignancy, immobility, and inherited clotting disorders.

3. Clinical Manifestations and Presentation
- Identify key signs and symptoms for DVT, including leg swelling, pain, and erythema, and for PE, such as dyspnea, chest pain, and hemoptysis.
- Recognize how to differentiate between DVT and PE based on clinical presentation and risk factors.

4. Diagnostic Criteria and Tools
- Familiarize yourself with the diagnostic modalities available, such as ultrasound for DVT and CT pulmonary angiography for PE.
- Learn about risk stratification tools like the Wells Criteria and the Pulmonary Embolism Rule-out Criteria (PERC).

5. Initial Management Strategies
- Understand evidence-based approaches for immediate management, including anticoagulation therapy and supportive care.
- Explore the indications for pharmacologic thrombolysis and mechanical thrombectomy.

6. Definitive Management Approaches
- Examine long-term treatment options, such as vitamin K antagonists and direct oral anticoagulants (DOACs).
- Evaluate the criteria for treatment duration and the role of inferior vena cava (IVC) filters.

7. Complications and Prognosis
- Discuss potential complications like post-thrombotic syndrome, chronic thromboembolic pulmonary hypertension, and recurrent VTE events.
- Consider prognostic factors, including the presence of comorbid conditions, the extent of clot burden, and response to initial treatment.

Table of Contents:
0:00 Lab
0:07 Venous Thromboembolism Introduction
0:14 Pathophysiology of DVT
5:01 Issues with DVT
6:03 Diagnostic Approach to DVT
9:09 Treatment of DVT
10:34 Pathophysiology of Pulmonary Embolism
11:59 Issues with Pulmonary Embolism
14:23 Diagnostic Approach to Pulmonary Embolism
20:39 Treatment of Pulmonary Embolism
23:24 Comment, Like, SUBSCRIBE!

Retired Ninja Nerd Lectures:

#ninjanerd #respiratory #venousthromboembolism

[lyuboslavlichev]

I can say for sure that the new type of video lectures are much less time consuming and very optimal ! Good job with that !

[sensorsports]

Very informative lecture, thanks. I like the new format with slides instead of the whiteboard. Especially because you can easily add real lab data, like the ECG, CTPA, and the Echo

[hammbaby]

got my income tax today, and I signed up to be a member so I can use yalls diagrams and notes now!! thanks ninja nerd and team

[adambahar]

Thanks very much for the great explanation! but the truth is that the reason that I choose to watch your videos and study from your explanations is that I really love the interaction with you on the white board... there are many other platforms that have PPX and the teacher just reads whats written... please back to original videos... thanks again!

[Kcfk]

Zach I can’t describe how excited I become when I see you. That’s when I realize that I will be learning some new stuff and that makes me happy.

[tonystarkim]

Sir board and marker was best

This one is also good. But it would be awesome if we do on the board marker....

[SamanPiroti]

Great video and presentation Dr. Zach! Thank you so much!

[Samar-uxbr]

pls pls don't adopt this method, except when u need it to explain something hard to draw or in the questions and cases 😫

we accustomed u as a legend😢

You are the best pls stay the best 😔💔

[julelaynecurry]

this was by far the best explanation I've heard of this topic!! Thanks so much

[michigan]

You seriously are the best! This video is super helpful!

[Drmohammedhidar]

جزاكم الله خيرا كثيرا و حفظكم من كل شر و سوء

[albuquerquenanda]

loooved this type of video too <3 miss the board but could totally get used to this
thank u so much!

[zubairulhassan]

Hello sir actually about 1 month ago I got a your video lecture about DVT and PE but now I can’t found those videos

[catahuanco]

At around minute 4:55 you mentioned Homan’s sign but you don’t go over how to perform/elicit it or when to perform the test. Also, you don’t mentioned if it is specific/sensitive.

[OrenoseGodwin]

Thank you for the explanation, , it's so helpful

[tmu]

really appreciate !! by med student from Taiwan

[medicalmasti]

East or west, our Ninja nerd is the best

[marwamustafaadam]

As always very informative thank you so much ❤❤

[jordangiono]

Please what’s the mechanism of chest pain in pulmonary embolism ?

[hazaralaabed]

Such outstanding development in your videos regarding quality and time. Keep up the amazing videos and good luck 😆