Rheumatology - Mastering the labs 🧪 - Antinuclear antibodies (ANA)

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Antinuclear antibody is positive in 1 out of every 9 females.
ANA is reported in tiers that are reported in numbers that double (1:40, 1:80, 1:160, 1:320,...etc).

The higher the ANA titer, the more antibodies in the serum, and the more likely the patient has an autoimmune disease.

However, antinuclear antibodies (ANA) do NOT correlate with disease activity or symptoms severity.

Taking a detailed medical history from a Rheumatology patient is critical because rheumatological diseases can affect any body system (extra-articular manifestation).

In this video, we will talk about quick hints on Osteoarthritis, Rheumatoid Arthritis, Systemic lupus erythromatosis (SLE), scleroderma, sjögren syndrome, and others.

Books that I used:

-Disclaimer 1: I am not a physician...If you have symptoms, talk to your doctor.

-Disclaimer 2: I use affiliate links.

Don't forget the classic rheumatology triad: joint pain, stiffness, and loss of function.

[bardacha]

This dude is genius. I am PhD but when I will have kids I will not send them to Harvard Medical School but to Medicosis Perfectionalis. You are extremely talented to explain medical course like no one else. Where could I obtain your materials (pdf or ppt) ?

[lovelovevon]

He makes education fun. I love his videos

[miqrib]

The symphonic mnemonic for the Anti-Ro and Anti-La is the best explanation EVER. Pulizer prize worthy. Hats off.

[heal-thee]

When I'm down about my condition I just come and listen to your videos, nothing like learning and laughing to get a quick pick-me-up!

[rittenbrake]

6:33 "shut up it has nothing to do with the symptoms or the severity" dead 😂😂😂😂😂 Laugh die me bro u r funny

[alaaaitaissa]

Just imagine having a guy like this teaching u
U cant just not love learning
❤❤

[umtameim]

I used to listening to one of the greatest professors in Egypt but I think I'll take a break while enjoying this rheumatology playlist.🌹thanks.

[raissapalmeira]

Very good! I'm a medical student from Brazil and I'm really enjoying your videos. Do not stop making them!

[faialnashmi]

Your explanation to the number of positive titers alone is great. Thank you again

[foodfood]

Mashallah, i am laughing so hard. I love your approach and very informative. May Allah protect you.

[zjengle]

Ah ha ha ha! As a lab tech who gets driven INSANE by the number of people getting unnecessary ANA tests, I found your commentary both accurate and hilarious 😂

[Rabbab-hc]

Thanks a ton for simplifying the topics to the basics . 🙏🙏🙏

[juliahernandez]

I bet this guy is so fun to hang out with! You are hilarious!

[skyberg]

Dude the quality of your videos are up in the clouds :) Well done 🥳

[karlint]

Adding one comment @11:04. (By the way, your lectures are flipping awesome). You said Anti-dsDNA is negative in drug-induced lupus, which is GENERALLY the case. But for drug-induced lupus caused by a TNF-alpha blocker (currently the most common cause of DIL these days), the Anti-dsDNA will be POSITIVE. Very important for those people who it affects!!

[michelelee]

Lol....absolutely love your approach. I laughed several times during your lecture. You’ve helped me understand more about the test, when I felt completely clueless. I have several symptoms, along with labs showing a high sed rate (53mm) and low white blood cells. My ana results are 1:80, and to my knowledge, that number is considered “weak/borderline positive”. I’m a bit confused with what that means exactly. Please help. Thank you:)

[armylife]

I’m glad you make these videos make me waste time in a good way :) thanks

[carlikieran]

Ha that was not only informative but funny and well explained. My rheumatologist suspects I have reactive arthritis but after a positive ana but negative further tests on autoimmune antibodies I was still worried about the ana positive. I feel quite comforted now that I may just be 1 of the 9. Also great to know pattern is not of use, I will rest my thumbs now. Thank you, wish you were my rhumey 👍😁

[armylife]

I have a question I want to be a nurse when I grow up, do I have to learn about almost all the diseases? If so I’m getting started right now with you I can’t remember anything but your videos make me remember everything in a fun way so I’m glad and thankful for everything you do keep up the good work

[sharvaridaithankar]

Thankyou sir...your videos are such a boon..😊