How electrospray ionization works

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What is electrospray ionization?
How does ESI work?
How to stabilize an electrospray?
ESI stands for Electro-Spray Ionization.
Ionization efficiency and ionization stability are important in mass spectrometry because the quality of the data depends ion the quality of the spray.
Electrospray and nano-electrospray are used for proteomics and metabolomics. Scientists and analytical chemists invest a lot of their time to get stable sprays.
I made and filmed an electrospray to show what is does when is stable, and what happens when it is unstable. This video is a hands-on introduction to electrospray ionization.

Professional electrospray and nano-electrospray solutions:

nano-electrospray emitters:

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Thanks a lot for the video! I'm a Chemistry undergrad and I have a test this week on Mass Spectroscopy, this helped me grasp how this ionization technique works :D

lhmavila
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I really enjoyed that u were having fun while explaining this. Good job.

wordsbyruthie
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This is the best ESO expansion i heard so far, I hope we will see more videos in the near future.
Thanks a lot!

gizmogizmo
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Thank you so much there's not a lot of good videos on electrospray ionisation I hope it covers everything on my test

ninjadog
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Great representation, it made easy to understand 👍👍

SanDiprtv
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Beautiful explanation and figures… mesmerizing

AlphaNumeric
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What an interesting video. Thank you for this content, and hope to see more from you.

alexb
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fun way to learn thank you for making it interesting

anwaralmajed
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Hi interesting video i work as spectrometer in hplc, particularly metabolomic. I interesting in bioinformátic to metabolomic. Thanks again

edgarestrellaparra
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The voltage needed to create the Tyler cone is it what we call the Fragmentor/fragmentation voltage?

sanaol-tpgn
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Wonderful Video! Thank you so much for this!

ronbessler
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Could u pls explain what happens when vinegar is added

srirampmna
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Yeah, now I know how the world works. Thank you for the vid.

FreedomAddicted
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I want to know about the negative electrospray ionization. Why corona discharge occurs in detail !!

chosy-utxl
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Thanks for the video!! Great knowledge and very helpful!!

javydemiguel
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a really good explanation! thank you so much! :))))

_han_da__
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Buenísimo, haha y la referencia al unicornio en microfluidos

fabzyL
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have you done .nano cellulose spraying

lifeisgood
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The video is really interesting and easy to understand . Could u please explain why ESI is best suitable for analysis of polar compounds

srirampmna
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For chain ejection long molecules are rejected due to what?

meganpass