Can We Use Antibodies to Treat Covid-19?

Potential vaccines for the coronavirus are all over the news right now, and we all hope that a safe an effective vaccine is developed soon. But vaccines aren't the only tool in the pipeline. Right now there's a lot of research happening around antibody treatments. When you get sick, your immune system produces antibodies to help fight off illness. Can we use these antibodies from recovered coronavirus patients to create drugs that help currently infected people fight the infection? We look at the research and the evidence around these treatments.

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#healthcaretriage #vaccine #covid-19

[Liberator]

Why isn't this channel have more than a million subs... I'm getting sick of seeing misinformation everywhere. Thanks for the info sir. 👍🙂

[teevannel]

I received this treatment and recovered nicely at home.

[rosemaryklauscher]

I first read antibodies as antibiotics, and was very puzzled. This makes much more sense.

[trisstunes]

wouldn't natural antibodies also be man-made? 👀

[Unsensitive]

Not from a factory, but i donated convalescent plasma 3 times for covid. Supposedly saving up to 15 people.

Not donating again though. I need to resume blood donations to reduce my iron level. They won't let you do both, nor take a lil extra blood when doing the plasma donation.

Gotta think of my own long term health.

[amschmarvelous]

Testing! I feel like a it's a terrible weak point in our response. I went to a pop up testing site after exposure and it took 13 days to get results. I went to a doctor referral test when I got a sore throat and had results the following day. We need to focus resources on processing tests.

[mikemartin]

You all should consider looking into Agenus (Agen). The company has been around since 1994. They’ve had a rocky road in the past but they now have gotten it together.


They’re an immuno-therapy company but they also produce cell therapy (INKT’S), through their subsidiary company Agentus and they also produce vaccines.

They also have the most powerful adjuvant (QS-21) on the market.

Their main product and near future revenue generators are their PD-1 and CTLA-4 CPMS. Both are currently fast tracked for second line cervical cancer and have currently initiated a rolling BLA submission. The data is compelling and suggests that their PD-1 is as good if not, better than Merck’s Pembro (Keytruda) in CC. And in combination, it’s definitely superior to Keytruda in CC. Projected revenue for the drugs will be around ~165M domestically only. They have also partnered with a chinese pharma company called Betta pharmaceuticals for international rights in greater China. Agenus will be receiving milestone and royalty payments accordingly. Expansion of these two drugs will yield higher revenue. They’re also looking into partnering in Europe. Projected domestic and international revenue could be significantly higher than the ~165m I quoted for domestic sales.

However, the biggest product they may have could be a potential multi blockbuster which is their next generation CTLA-4 1181. This is what most investors are banking on. They’re already seeing CR’s (complete responses) in Phase 1. It’s showing more than 70 percent clinical benefit (not to be confused with ORR.)

Ctla-4 is notorious for being toxic but agenus has manufacturing a very tolerable version that has low toxicity levels. This is huge.

I believe they have 10 CPMS in the clinic and somewhere around 10 in preclinical. They have partnerships with GILEAD, MERCK, GLAXOSMITHKLINE, INCYTE AND BETTA PHARMACEUTICALS.
I’ve mentioned most of the pros on the company. The only con is, they need capital to market the product once approved and for label expansion.

They may need to dilute or continue to do what they’ve been doing successfully which is partnering up with someone for a cash injection. But dilution at this stage may be looked at in a positive light considering their active pipeline. I hope you all enjoyed my synopsis. GLTA!!

[SRR-rhid]

I have a question. When you say influenza vaccine different from measels vaccine, in what way do you mean it? Is it that influenza is given every year unlike measels, or that influenza has less efficacy than measels?

[therabbithat]

interacting with content to impress algorithm and spread video

[mathiasniemeier]

I took Rituxen for 2 years weekly. Doing great! Can I use this for travel?

[truthseekerjen]

I got this antibody infusion yesterday in the er. It saved my life!

[ShaunCKennedyAuthor]

Strange question: if we are aware of antibodies that effectively disable a virus, is there any reason we couldn't engineer a bacteria to produce that antibody and then spread that bacteria all over to release antibodies everywhere and get rid of the virus?

[onthecover]

Fun fact: If we heal people, they will, indeed, be healed

[jdg]

Just wondering. Is Sam the Surgeon Admiral an inside joke playing on the fact that the US Surgeon General is actually an admiral?

[beaudavis]

Just give me the vaccine and I will be fine.