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Psychedelic Science in 2020 | An overview of the psychedelic renaissance
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We are in the midst of a huge resurgence of scientific interest in psychedelic substances. They are now being shown to have great potential for a variety of applications - from treating mental conditions, to enhancing our meditation practice, to increasing our connection to nature.
In this video, I give a broad overview of the latest exciting psychedelic research being conducted at leading institutions across the globe!
Don't forget to follow me on social media for all the latest updates:
More info about the host:
Manesh Girn is a Neuroscience PhD student at McGill University and has been lead or co-author on over a dozen scientific publications and book chapters on topics including psychedelics, meditation, daydreaming, and brain networks.
Manesh currently has ongoing collaborations with Robin Carhart-Harris and others at the Imperial College Center for Psychedelic Research and is investigating the brain changes underlying psilocybin, LSD, and DMT.
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On popular request, here are the papers I refer to in this video (in no particular order):
1. Carhart-Harris, R.L., et al., Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry, 2016. 3(7): p. 619-627.
2. Lyons, T. and R.L. Carhart-Harris, Increased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression. Journal of Psychopharmacology, 2018. 32(7): p. 811-819.
3. Johnson, M.W., et al., Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. Pharmacology & therapeutics, 2019. 197: p. 83-102.
4. Griffiths, R.R., et al., Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of psychopharmacology, 2016. 30(12): p. 1181-1197.
5. Johnson, M.W., et al., Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 2014. 28(11): p. 983-992.
6. MacLean, K.A., M.W. Johnson, and R.R. Griffiths, Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness. Journal of Psychopharmacology, 2011. 25(11): p. 1453-1461.
7. Griffiths, R.R., et al., Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later. Journal of Psychopharmacology, 2008. 22(6): p. 621-632.
8. Griffiths, R.R., et al., Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Psychopharmacology, 2006. 187(3): p. 268-283.
9. Carhart-Harris, R.L. and K.J. Friston, REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics. Pharmacological Reviews, 2019. 71(3): p. 316-344.
10. Carhart-Harris, R.L., et al., Neural correlates of the LSD experience revealed by multimodal neuroimaging. Proceedings of the National Academy of Sciences, 2016. 113(17): p. 4853-4858.
11. Carhart-Harris, R.L., et al., Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin. Proceedings of the National Academy of Sciences, 2012. 109(6): p. 2138-2143.
12. Krebs, T.S. and P.-Ø. Johansen, Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials. Journal of Psychopharmacology, 2012. 26(7): p. 994-1002.
13. Girn, M., et al., Updating the dynamic framework of thought: Creativity and psychedelics. NeuroImage, 2020: p. 116726.
14. Baggott, M.J., Psychedelics and creativity: a review of the quantitative literature. PeerJ PrePrints, 2015. 3: p. e1202v1.
15. Ross, S., et al., Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. Journal of psychopharmacology, 2016. 30(12): p. 1165-1180.
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