Liver Metabolism: Carbohydrates, Amino Acids & Lipids

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In this lecture, EKG is going to summarise the liver metabolism of carbohydrates, amino acids, and lipids. We're going to break down the big picture by connecting the 3 main sources of fuel (glucose, amino acids, and fatty acids) and the various fates they can take in the liver. We're going to look at catabolic reactions and anabolic reactions. 

Lecture Overview:
0:00 Intro
0:28 3 Main Sources of Fuel Review
1:25 Carbohydrate Metabolism Pathways
6:50 Amino Acid Metabolism Pathways
9:55 Lipid Metabolism Pathways

✏️ All diagrams were made by EKG.

Lecture Source: Nelson, D. L., & Cox, M. (2017). Principles Biochem 7e (International Ed). Macmillan Publishers.
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#Livermetabolism #Metabolism #Biochemistry

[barzeit]

Thank you, this video connected a lot of dots for me which was exactly what I needed. Have a great day! 💕

[mohdkh]

Thank you for this very amazing the best explains for metabolism ever ❤️

[ayannalynn]

I absolutely love your video ❤ I’m studying for my national registration exam to be a registered dietitian. This is so helpful! You are awesome at explaining complex topics in an easy digestible way. Thanks 😊

[Sam_]

This is amazing presentation. Thank you for all your efforts

[Alaia]

So helpful video better than my own tutor lecture

[Win-xq]

Thanks for this wonderful explanation 🤗

[dombarton]

The human body will always have glucose available when it needs it regardless of carbohydrate intake..since carbohydrates are the only non essential macro nutrient..humans instead use gluconeogenesis . We only require around 4 to 5 gms at any given time. Our brains run perfectly fine on ketone bodies. The body prefers ketones over glucose...many believe that the human body prefers glucose..WRONG...it tries to rid itself of glucose very quickly and goes to great lengths to use it up first..that is the reason why its " preferred" the same goes for Alcohol...it will be used up instead of glucose because it has more energy per gram than glucose but is TOXIC. So it will be "preferred even more so" In summary preferential treatment by the human body is NOT due to because it actually likes these forms of energy...it wants to rid itself quickly of these chemicals.
During the third trimester of pregnancy and at birth, both mom and foetus are naturally in a state of mild ketosis. Within the first few days after birth, babies adapt to using their fat stores as their primary fuel-source, and begin to produce more ketones.
Ketones are the ideal source of energy for all humans. Glucose is required by only a few processes in the human body and it can beautifully manufacture what it needs.