filmov
tv
Voltage gated Ca++ Channel
Показать описание
I discuss how a voltage gate Na+ channel works, and how it is blocked by tetrodotoxin (TTX) in newts of California. Newts have evolved mutations in Domain III and Domain IV of voltage-gated Na+ Channels (Nav1.4) to allow them to use the deadly TTX as deterrent to predators. Newts are however eaten by garter snakes in the Bay Area of California, which have evolved mutations in Voltage-gated Na+ Channels, in the same Domains of the DNA code as the newts; Credits: Writing, Animation, Production: Barry Sinervo, University of California, Santa Cruz, key grip (on a reality check of the facts): Chris Feldman University of Nevada Reno; Citation: The animation is inspired by the Figure 11-37 in Alberts, B. (2002). Molecular Biology of the Cell. United States: Garland, but in this case presented as an animation to aid in understanding. The narration is based on Albert's description of the Figure 11.37 .in Alberts's textbook.