How does Dapagliflozin work? Understanding SGLT2 inhibitors.

The video contains a simple and visual explanation of how ‎Canagliflozin ‎Empagliflozin and Dapagliflozin, SGLT2 inhibitors, work to get the kidneys to excrete glucose into the urine. We cover some basics about how the nephron works and look in detail at the action of SGLT2 inhibitors on the sodium-glucose transport protein 2 (SGLT2) in the proximal tubule. We also talk about the indications and adverse effects.

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DISCLAIMER: This video is for education and entertainment only, and is not medical advice. This video should NOT be used for medical advice or to guide clinical practice. The Zero to Finals content should not be used in any way to guide medical decision making. Zero to Finals takes no responsibility for any actions taken or not taken based on the information provided. Local and national guidelines and senior clinicians are there to help you make decisions, not YouTube videos. If you need medical advice or information, seek it from an appropriately trained and licenced doctor or healthcare provider that can address your individual needs. Zero to Finals cannot guarantee the accuracy of information in this video. Please highlight any errors you notice in the comments below - thank you.

[majdoleena.]

i don't what to say really. the amount of work u put into your videos and content and the knowledge in such a short amount of time, it amazes me. honestly THANK YOU so much for your amazing efforts :'( <3

[sureshspirit]

I am not a Medical Student, but an Diabetic Patient for last 4 years, The Doctor prescribed me this medicine, but didn't cautioned me of the side effect of Urinary Tract Infection (UTI), and i stopped this medicine. Now after seeing your Video, I know and understand the reason. Thanks for Sharing the Video.

[erica]

It certainly is an easy-to-understand video. I appreciate your hard work and effort in making such a great video:) It improved my understanding of SGLT-2 inhibitors.

[db]

Hi, great video. Would it be possible for you to explain why dapaglifloxin has now been indicated for use in heart failure patients. Thank you

[uttamsingh]

In this conversation I totally grab the knowledge about dapagliflozin molecules.Thank you so much.

[JobairEEE]

It's really helpful. I am not a medical/pharmacology or related subjects student but it seem I have understand all the points that you have mentioned in the video.

[vimalvettry]

Its very simple and easy to learn and you Now i clearly understand

[aashimasharma]

Thankyou so much for putting in so much efforts to make us understand the concepts so easily. I totally get the topic now :)

[michaellynch]

Just what I was looking for! Thank you for doing this work of putting this video together.

[stevelepak]

Thank you so much for this video. It really helped me solidify my knowledge about SGLT-2 inhibitors.

[Shivanand]

Good job. Using this to study for my commonly used drugs test in pharmacy school

[therapontsakouridis]

Hallo.I like this video because it explains simply and clearly explains the mechanism of action of SGLT2 inhibitors.

[aungseoulhtoon]

So easy to understand its actions after seeing your video 🤩

[komaraiahkanakam]

Thank you very much Doctor for the Useful medical Information 🎉👍🎉

[yordigiordana]

Excellent video! but how does it help non-diabetic patients with CKD (Iga Nephropathy? Thank you.

[saraisa]

Your explanation is so good that I see your video on x2 and I wish there is x3 and still understand everything 😍

[ppumpkin]

Great video. But why does serum creatinine, and urine protein and albumin increase while taking Farxiga?

[SuperLittleTyke]

I was prescribed Dapagliflozin along with several other medications to treat heart failure with reduced ejection fraction (25% to 35%). The combination of drugs I take really has had a very marked improvement in my health. I am 78, male. I have been Type II diabetic for over 10 years, but it was diet controlled throughout. I never needed any medication. I was declared to be in remission about three years ago. I also strove to lose a lot of weight by accurately counting calories of everything I consumed. My weight went from 82kg to currently 64kg in ten years. I am 1.56m tall.

[davidallegro]

Not a student, however very informative. Thank you just received a suggestion from my doctor.

[djou]

Thank you for this amazing explanation