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Are Challenge Trials Ethical for COVID-19? with Richard Yetter Chappell @ Pod of Asclepius
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Richard Yetter Chappell (University of Miami) discusses his recent article (with Peter Singer) on the ethics of a COVID-19 challenge trial.
0:00 Intro
0:19 The ethics of challenge trials
1:17 Hello to Richard Yetter Chappell
2:12 What sparked the challenge trial article?
2:52 Disconnect: Social ethics vs bio-ethics
4:42 What is a challenge trial?
6:35 What was the Richard Chappell / Peter Singer position of challenge trial?
8:00 Differential risk: trial subjects vs general public
9:55 Word of the day: "ex-ante" risk
10:48 What are the counter arguments to challenge trials?
13:00 Overton window of philosophical positions
14:35 Is understanding risk sufficient for informed patient consent?
18:00 GI Joe Fallacy
22:00 Is understanding benefits necessary for informed patient consent?
23:25 Ethics of inconclusive studies
25:55 Ethics of Type 1 vs Type 2 statistical errors
30:35 Further reading
0:00 Intro
0:19 The ethics of challenge trials
1:17 Hello to Richard Yetter Chappell
2:12 What sparked the challenge trial article?
2:52 Disconnect: Social ethics vs bio-ethics
4:42 What is a challenge trial?
6:35 What was the Richard Chappell / Peter Singer position of challenge trial?
8:00 Differential risk: trial subjects vs general public
9:55 Word of the day: "ex-ante" risk
10:48 What are the counter arguments to challenge trials?
13:00 Overton window of philosophical positions
14:35 Is understanding risk sufficient for informed patient consent?
18:00 GI Joe Fallacy
22:00 Is understanding benefits necessary for informed patient consent?
23:25 Ethics of inconclusive studies
25:55 Ethics of Type 1 vs Type 2 statistical errors
30:35 Further reading
0:33:32
Are Challenge Trials Ethical for COVID-19? with Richard Yetter Chappell @ Pod of Asclepius
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Why Vaccine Challenge Trials Are So Controversial
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Coronavirus vaccine: What are human challenge trials? - BBC News
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Ethical Controversies around Human Challenge Studies
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The Ethics of Human Challenge Trials During Covid-19
0:00:53
Dr. Marc Lipsitch: The Basics of Human Challenge Trials
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Dr. Marc Lipsitch: Maximizing the Scientific Value of Human Challenge Trials
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Controversial ‘Challenge Trials’ In UK Will Infect Healthy Patients With COVID | TODAY
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Ethical Dilemmas in Modern Leadership | Leading By Example with Dr. Von
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The Ethics of Human Challenge Studies Part - 1: Challenge trials generally
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How COVID-19 human challenge trials work -- and why I volunteered | Sophie Rose
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What Human Challenge Trials Can Teach Us -Nir Eyal | The Open Mind
0:05:38
Would You Sign Up For a COVID-19 Human Challenge Trial?
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Dr. Cameron Wolfe: The Unique Values of Human Challenge Trials
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The science behind 'Challenge Trials'
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Dr. Nir Eyal: Approach Challenge Trials with an Open Mind
1:02:20
Coronavirus Conversations: The Science and Ethics of Human Challenge Trials for COVID-19
0:04:44
Former FDA chief Scott Gottlieb on ethics of human challenge trials for Covid-19 vaccine
0:53:18
Vaccine policies and challenge trials: the ethics of relative risk in public health
0:02:00
WHO looks into concerns related to human challenge trials used for COVID-19 vaccine development
0:38:10
Human Challenge studies
0:02:12
What drives people to participate in human challenge trials?
1:33:12
The Ethics of Human Challenge Studies Part - 2: COVID-19 Challenge Trials
0:02:00
Interview with Ethicist Prof Peter Singer on the ethics and challenges of human challenge trials
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