New Study: The Value of Collagen Protein | Educational Video | Biolayne

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I had elbows joint pain that didn't go away for months, once started taking 20g of collagen peptides daily the pain completely gone in weeks and never came back. My skin also looks slighty better. It might be placebo effect but as long as the pain is gone and not coming back i will continue to take it.

ronishternbach
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Layne, please don't be that guy. The study has no mention of collagen peptides, only collagen, an important distiction because collagen is notoriously hard to digest (it's a proline rich protein like gluten and casein), and we don't know which collagen was provided. Some have as low as 27% absorption rate, while hydrolyzed collagen has 90%+. It would be interesting to see the difference with collagen peptides.

Our gut can more easily absorb peptides, dipeptides and even tripeptides than longer chain aminoacids, so it's not like a protein's amino profile is the only metric of its usefulness, its digestibility should be considered.

As you know, collagen is our body's most abundant protein (25-35% total protein), our joints are 85-90% collagen, our skin is 70-80% collagen, cartillage is 50%, bones are 30-40% and connective tissue is only 25-35%. Skeletal muscles, on the other hand, are barely 1% collagen, so any study that "debunks" myofibrillar protein synthesis is mostly wasting time. I mean, was there any metric of connective tissue damage during the exercise?

Compared to whey protein, collagen is going to suck for muscle protein synthesis. On the other hand, whey protein has barely any glycine and proline compared to collagen (even if they can be obtained from its other aminoacids, it takes effort). So for the purpose of joints, skin, cartillage, bones and connective tissue health, collagen peptides still make a lot of sense.

danfg
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This study only looks at the acute effect of a single administration of collagen in the MUSCLE connective tissue. It says nothing about the effect of chronic supplementation on joint and cartilage connective tissue.

jc
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Hi Layne, just FYI, your opening panel at 00:04 says "Does training time matter when fasting?" vs collagen protein.

SelfAbridged
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Layne, it's worth noting that recent studies suggest it's actually collagen peptides—small molecular weight collagen—that can boost collagen production in skin and connective tissue, not whole collagen. Might be worth revisiting the topic with this in mind!

andreinikiforov
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Layne, you may want to review the research by the folks at Gelita, showing that the molecular weights of specific collagen peptides increases muscle mass and strength in both young and old. They also have a nice study showing that their specific molecular weight peptides also induce multiple protein synthesis pathways when compared to whey protein.

MoodMindMemory
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I took collagen alongside whey when after my surgeries. The incision closed fast and my muscle mass did not decrease as much during recovery

ivandavila
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Collagen is absorbed as di and tri peptides, not only as individual amino acids. More substrate also shifts the chemical balance towards the end product and makes it easier to catalyze a chemical reaction.

blackjack
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Understanding protein digestion is the reason I was never a believer in collagen peptides. However, because of so many anecdotal reports, I decided I would try collagen peptides. My hair and nails grow faster. My skin complexion looks better. My joints feel ALOT better while lifting and post workout; noticeably better. Due to this, I’ve bought more bovine collagen peptides. I know, it’s my anecdote, but like I said, I “poo pooed” the idea of collagen for years because of my understanding of protein digestion. Now I continue to take 10-20g of collagen peptides a day.

ryankittle
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I make my own beef broth from grass raised beef bones.
You can see a thick layer of cologne that rises to the top. Velvety texture, great flavor etc.
I suggest making your own.

johnnyripple
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Hey Layne, love your videos. Thankyou!

Also. Can I ask what mic you use for your videos??

calvinwesthovens
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Really respect your scientific approach. I know the video was looking at collagen supplements for connective tissue - but as you mentioned early on, many women are taking collagen for hair, skin and nails - more of a beauty aspect. Any thoughts on that either way? Thx always.

angelauk
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Great video! Many thanks for shariing Layne

azdhan
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While I don't expect collagen supps to work, I'm curious if the stimulus was sufficient. For instance, were subjects doing something like kneesovertoesguy's knee program? Was it done over long enough period to see results?

platosbeard
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The study participant were young also study was very small, n=45. Do you think we would similar results in an older population where collagen synthesis is reduced. Also how is it we see studies which show improved joint pain and mobility and improved skin elasticity with collagen supplementation if supplementation does not impact collagen synthesis?

Dan-jirx
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You were immediately critical of collagen supplements when they came out? Dude, I remember seeing them at GNC in 1992...when you were 10 years old. Props to you being that knowledgeable so young!

inkwell
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Did the study account for vitamin c intake as well. I’ve heard through some sources that it’s needed for collagen synthesis/production so just wondering about that and your take on if that’s true or not

mike-fqth
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Hey Layne,
And what about benefits for skin, hair and nails? Is it worth it or no?

howlpendragon
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I mix a full spectrum protein shake and include collagen, sometime collagen type II, and sometimes type I and III. So hypothetically it may work because of the type of collagen and because the leucin in my protein will activate my collagen. So you are right, but my real life experience could also be. More studies needed.

wennerstierna
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What about for skin health? I've been taking 11g per day and it's done a bit to firm up my skin quite a bit

burner