Endometriosis is a disease of immune dysfunction

Endometriosis is an inflammatory disease that’s affected by hormones but is not caused by hormones. Instead, endometriosis is, at least in part, a disease of immune dysfunction.

In this episode, Lara discusses some of the new endometriosis research, including:
- the link with genes that increase the risk of autoimmune disease
- the role of a bacterial toxin called lipopolysaccharide or LPS, and
- new targets for natural immune-modulating treatment.

Links to:

[iamthat]

Thanks Lara, I read your book 4 years ago, started your protocol and cut gluten, most dairy (Not organic NZ butter) and took Zinc etc. The pain decreased almost 100%! I then had surgery 6 months later which I had told Dr's I suspected I hade Endo and of course they all denied untill surgery. Since then, I have trialed fasting whcih helps restart immune system and resets good bacteria and starves the bad bacteria. But noting beats what a Dry Fast did. I did 2x 48 Dry fasts in 1 month and WOW! it bought inflammation down and was very healing and noticeable to even a new burn I had on arm. Can't say I would recommend dry fasts to everyone as you would need to build up and try a 2-3 day water fast before hand. But all these many natural things will help. Hope this helps someone, God Bless💖

[poolspattaya]

Here in S.E. Asia this topic isn’t talked about enough. My wife has stage 4 endo and will go for surgery this month. I wish there were more experts like you promoting these science based discussions because here a lot of the FOR PROFIT medical industry just salivates at the profits by talking up last century’s surgery only approaches... for a condition that effects nearly 10% of all women at some degree, this is insanity. Here’s cheering for change

[amazinggrace]

Thank you. As a Endometriosis sufferer this makes perfect sense to me. I was diagnosed with Endometriosis at the age of 24 in 1984. Over the next ten years my endometriosis got so bad that I needed a hysterectomy, plus removal of my ovaries, fallopian tubes and appendix. I also had endometriosis on my bowel. The adhesions and lesions were so severe, that they stuck to my bowel causing a twisted bowel. On two occasions I had emergency, life saving bowel surgery to divide the adhesions. During this time I was on medication, firstly a progesterone treatment and then Danazol for the last 6 years. I didn’t have a period from the age of 24. Even on Danazol my Endometriosis worsened. My Gynaecologist was dumbfounded and couldn’t understand how I could end up with such an horrendous case of endometriosis whilst being on Danazol. The latest research answers that question. It’s taken most of my life to find a plausible answer. Thank you.👏👏👏👏

[Jejujejuzero]

Hello, hello, hello. Please respond to my comment. 😢😢 could you please do a video on Adenomyosis. The pain is horrible and the same as endometriosis, but Adenomyosis they recommend straight hysterectomy. This was an excellent video. I wish I had £50 million to give to do more research on this. I have never seen pain so horrible and traumatic. Prayers for all my endometriosis and Adenomyosis sisters.

[OZMAZZ]

I really dislike all the hypothetical scenarios. We need definitive answers.
I tried gluten free for two years and dairy free for 3 at the same time. I got way way worse.
This disease has so much to do with immune system modulation.
I believe it’s to do with an underlying MCAS. This condition gets triggered and gets worse with time.
Yes it maybe related to bacterial infection or even a parasite infection.
But all the maybes don’t help unfortunately.
It’s not genetic but perhaps a microbial
I wish there was more research into this, it’s almost like it’s on purpose that there is no research on it.
Women are paying thousands and spending their entire lives from one doctor to the next plus fertility treatments etc. what a cracking money maker.

I don’t know if this is something to look at but I think there maybe progesterone antibody involvement 🤷‍♀️ I could be wrong but I believe so many of us are allergic to progesterone that maybe where the immune response is coming from.

I developed my symptoms very young right after a tetanus shot. Again it maybe not related. But the same tetanus shot was implicated in the hcg that was found in them in Kenya, Philippines and Africa. Who knows where else?
We need immunology to look into this.
It’s not a hormonal issue, it’s immune issue.

[kukiazz]

Love your work Dr Lara Briden. The information you have provided here is so thorough so in-depth & most importantly life changing for women with this disease ❤ The info on your website is also next level too! Could you possibly do a similar video but on Adenomyosis?🙏?
Bless you 🙏

[stk]

My endo symptoms appeared postpartum with my first when I was 33. I later started having anaphylactic reactions and was diagnosed with idiopathic anaphylaxis. After excision surgery (I was stage4) my histamine issues disappeared. I’ve always known there was an immune link! My allergists never agreed or had any knowledge about it but this is validating. Most medical professionals are in the dark when it comes to endometriosis, in my experience. Can’t wait for more information to be discovered.

[IzzyBJonesxox]

Definitely a genetic link in my case. On my father's side I have an aunty with fibromyalgia who has 2 children with autoimmune diseases. Another aunt had her thyroid out and the other has 1 child with ibs, 1 with aspergers and another had her thyroid out. My grandmother was known to be in bed for days at a time so can only assume she also had endo.

[fallingstar]

I’m in so much pain. When I stop breathing, the pain stops.

[roisinmc]

This does not surprise me as I have endometriosis and many other autoimmune issues, allergies etc. In my late 20's ( I am now 44) I cut out all gluten, dairy and refined sugar and I have stuck to this. I don't eat rubbish gluten free alternatives though which are often just as inflammatory, I eat quite low carb and very few grains at all. Meat and lots of vegetables and some pulses, nuts, olives etc I don't drink alcohol since my early 30's either. It has not cured the endometriosis but has helped massively and I have not had any type of surgery for it. Prior to doing that I was off work for 2/3 days, bedridden shouting out in pain like I was in full blown labour, that is honestly what the cramps were like. I still have quite painful cramps but nowhere near to this level and only on day 1.

[SaritWorld]

This disease is so painful i remember a time i used to think that the strong natcotics that were prescribed and i thought those were sugar pills for this pain is untouchable.

[niyoleo]

You should speak more on the benefits of *castor oil packs* for the treatment of internal problems including the reproductive organ.

[sam_dough_]

This explains why sometimes I have flare ups worse than other times! Always felt symptoms were influenced by other factors

[muirgirl]

Great video. The bacterial contamination theory isn’t all that crazy when you consider that reactive arthritis is a well known and common event after chlamydia infection (not to mention the myriad immunologic complications that crop up with secondary syphilis).

I also think a lot of women on the hereditary hemochromatosis spectrum present w endo but the genetic testing is never done.

Personally I think endo is a metabolic disease process. Particularly when you consider the role of aldosterone in de novo lipogenesis.

[goldstar]

So glad women of the future are not going to have to suffer as generations of the past.
I am not even vindictive or mad that I have been sickly since I started womanhood now post menopause. It is wonderful to know in my own mind what happened to me.

[RaeRaesRaveReviews]

I never had gut issues until I started having endometriosis symptoms at age 36. Didnt even know I had it before then. Now that I had excision surgery, and have put a lot of effort into restoring my microbiome, my gut feels great. I eat gluten too :)

[shaundrarobinson]

Thank you for continuing to research and discuss this common, but constantly overlooked disease.
The suggestions from your books and blog have literally helped transform my life. Thank you for your dedication to helping women. ❤️❤️❤️

[patriciafalasca]

Thank you very much for this podcast and video, Lara. Wonderful information for someone who is tossing and turning with endo pain right now. Thank you!

[bedcrums]

Does this information apply to those with Adenomyosis as well?

[mandy]

Wow thanks so much for sharing. Even after having hysterectomy, I had to have another surgery for endometriosis. I am also diagnosed with psoriasitic arthritis. I was also told that I am border line lupus. I have often thought that they were all somehow connected