Best Friends Challenge with Justin Timberlake and Jessica Biel

Jessica Biel and Jimmy Fallon try to guess Justin Timberlake's responses to a series of random questions in a competition to see who really knows him best.

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The Tonight Show Starring Jimmy Fallon features hilarious highlights from the show including: comedy sketches, music parodies, celebrity interviews, ridiculous games, and, of course, Jimmy's Thank You Notes and hashtags! You'll also find behind the scenes videos and other great web exclusives.

Best Friends Challenge with Justin Timberlake and Jessica Biel

#BestFriendsChallenge
#JustinTimberlake
#JessicaBiel

[danielabucekova]

I love how Justin mouthed 'I love you' to Jessica, it was so cute! 😍

[ellie..bell]

Jimmy has a twinkle in his eye when JT is on his show! Definitely brotherhood!

[TheFollavoine]

A quiet Justin Timberlake is actually funnier than some other guests... just sayin’ 😆

[neerajjude]

Ryan Reynolds, Hugh Jackman and Jake Gyllenhaal need to play this game

[poop]

Jimmy was so hurt when Justin said his favorite cocktail was tequila mule

[justjac]

Justin and Jessica: Breathes*

Jimmy: BWAHAHHAHA OMG STOP PLEASE HAHAHHAHA

[netalevy]

I love how Justin got offended when jimmy didn’t know what a tequila mule was

[uikhan]

I wish I had the muscle definition in my arms that Jessica Biel has!!

[VINCINT]

It's not fair how attractive they are together

[Spidey]

JT and Jimmy Fallon have such a genuine Friendship.

[ArvinB_]

Lmao everyone be like “congrats on the marriage” when they’ve been married 7 years.

[HannahKristinaRayne]

Britney watching at home shouting out all the answers

[davidvaccaro]

Even though he didn't talk Justin Timberlake killed it tonight 🙌🏼🙌🏼

[adamaj]

So Jimmy and Jessica BOTH know Justin's safe word....interesting...

[kaylaabraham]

jimmy missed a perfect moment to say "we're perfectly nsync" at the end there

[han-ninglu]

3:40 Jimmy only got up to flex his shoes on them haters

[raimeyewens]

At 3:30 Jessica finds out Justin and jimmy are way closer than she thought.

[izzy_._t]

Poor Justin on voice rest. He could have used that for an audition for A Quiet Place! 😂

[nadjawmiller]

4:28 that moment when Jimmy and Justin looks at each other and then laugh again, I love it lmao

[darkness]

Jimmy left the desk just to show off those fresh kicks