Networks and Neurochemistry Measured with Paired Pulse TMS

Hosts: Professor Charlotte Stagg (University of Oxford) and Dr Roisin McMackin (Trinity College Dublin)

Short intracortical inhibition (SICI), measured using paired pulse TMS, is regularly employed to investigate motor cortex pathophysiology. Such studies have provided important supportive evidence of change in the balance between inhibition and excitation in many diseases. Although substantial information has been gathered to date about the neural networks and neurochemistry which give rise to SICI, many questions remain unanswered. In order to truly understand what SICI can tell us about motor cortex function and dysfunction, the existing evidence must be carefully considered and further investigations must be undertaken. In this webinar, Dr McMackin and Prof. Stagg will discuss what we do and do not know about the physiology underpinning SICI and how we can fill in the blanks for unanswered questions

[enokjamal]

Great lecture. I especially liked the clear explanation of SICI, ICF, LICI and IHI and GABA-ergic inhibition.