Click Chemistry (Nobel Prize 2022) - Periodic Table of Videos

The 2022 Nobel Prize in Chemistry is awarded to three scientists for pioneering "Click Chemistry".
More links and info in full description ↓↓↓

Featuring Martyn Poliakoff, Miriam O'Duill and Christopher Merrett.

The Nobel Prize in Chemistry 2022 was awarded jointly to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless "for the development of click chemistry and bioorthogonal chemistry"

This episode was also generously supported by The Gatsby Charitable Foundation

[thewilltheway]

This Nobel prize is a godsend because my project works with click chemistry. Now I don’t have to explain what that is to my colleagues because everyone knows now.

[tomwatts]

My undergrad literature review is on click chemistry - specifically the azide-alkyne reaction - so it was really great news to hear that three authors whose work I've been studying had won the prize!

[Djinn_Tonic]

Click chemistry with copper and azides!
I used it when i was graduating as a way to attach denaturated DNA to solids for later analytic use. That was 10 years ago, but I remember it as an interesting and very useful tool.
Well deserved Nobel prize!

[stevie-ray]

Even though I'm not a chemist & only have a rudimentary understanding from high-school (50yrs ago) & of course your great YT videos, I still find all these discoveries fascinating especially when they're so well explained by your presenters!

[sergiosaucedo]

As an immunologist I can say, Carolyn Bartozzi’s work has been crucial in the development of immunotherapy. A Nobel Prize very well deserved!

[abigaylegonzalez]

I’m an undergrad working on some organometallic synthesis, and purification is by far the hardest portion. After 20+ H-NMR spectra it’s easy to read and do data analysis. What is impossible is subliming my compound without breaking and frying it. So either I use liters of solvent testing what would clean the best or I keep burning it. Organometallics in GC/MS would even be more of a struggle with ordering the right column. One day I hope to publish my first paper and someone being able to extend it further with their 20+ years of experience

[MrHeroicDemon]

Almost 2 Million subs, i've been here since like 2009-2010. I was in Chem U 11 when I found this channel. Obsessed with all Brady's channels since.

[piplow]

Wooo keep the episodes coming guys! Thank you all

[RaunienTheFirst]

One of the projects I was involved with in my undergraduate studies involved the Cu(I)-catalysed azide-alkyne reaction. We were making ligands for metals with the intention that they could be dyes for solar cells. That is, the part that has an electron excited by being with a photon and pushes that electron into the circuitry.

[dylanvellut]

I did a click reaction for my studies 5 years ago. I was impressed by the expedient reactivity and the bright yellow insoluble product at the end. One of my best reports due to the simplicity of set up and purification process .

[JCtheMusicMan_]

Excellent video! I was only previously familiar with click-bait chemistry 😅 💜

[Pongant]

I can see why biologists are super excited about click chemistry. The whole setup reminded me of regular work in a biolab

[Veptis]

Hearing Brady asking the questions I have on my mind is usually reassuring. But now I am left with questions I didn't realize I had.

[ProfessorWaltherKotz]

In memory of Rolf Huisgen (1920-2020), who never got the attention he deserved.

[GuillotinedChemistry]

I enjoyed your colleagues' experiences and perspective with actual click chemistry reactions. So happy to see Dr. Sharpless that won it again... He seems to have never lost his curiosity and wonder. 😄

[theultimatereductionist]

Amazing that Barry Sharpless has worked for 52 years as a chemist, winning a Nobel Prize, TWICE, since losing sight in one eye!

[essentialgmbesttoday]

Your effort is to warranty your human's kind, it's warranty your humanity, honor and prize are an identical separate your knowledge from the whole- Your job is help to solve world's problem. it's help us, it's educate us - Congratulations! and keep working to find something to challenge the worlds.

[ginj]

I’m a student who still doesn’t know a lot about chemistry but I’m incredibly interested and these videos are continuing to introduce me into its amazing world I suffer from pretty bad ADHD and I struggle to concentrate but chemistry helps me out with concentration and I enjoy it so much happy I subbed you have a really calming voice and your way of explaining is amazing it’s unfortunate the uk education system for high school doesn’t do chemistry as much as other countries

[andreascasablancas]

Im a pharmacist/modeler so my chemistry isn't the best but I'd appreciate to know how can the alquine and azide groups can be easily added to biomolecules in the right place.

[AustralLabs]

Like key pairs matching in a search system - this is probably how ribossomes are so efficient in generating extremely low probability products - each catalytic locus is very low energy, but the chain is large an the combined energy of weak partial matches makes the chain termalize into a reaction.