Coronavirus Update With Peter Piot, MD, PhD

Peter Piot, MD, PhD, Director of The London School of Hygiene and Tropical Medicine is a legend in global health, having been involved in identification of HIV and Ebola virus in Africa. He was founding executive director of UNAIDS and Under Secretary-General of the United Nations from 1995 to 2008. He joins JAMA's Q&A series to discuss the global public health response to COVID-19 past, present, and future. Recorded January 28, 2021.

Topics discussed in this interview:
0:00 Welcome Peter Piot, MD, PhD
1:22 Reflecting on the pandemic and its surprises
4:20 Asymptomatic spread
6:49 Missed opportunity regarding masks?
8:19 Masks and reductions in flu reports
8:38 New variants and the vaccines
14:18 Should vaccine efforts target something other than the S protein?
17:16 New COVID-19 variant concerns
18:30 Single dose vaccine concerns
21:58 Vaccine rollouts in the UK
23:34 Current progress on treatments for COVID-19
29:41 Being a "long Hauler" with persistent symptoms
36:00 Addressing vaccine inequity
40:20 Have you been vaccinated?
41:29 Do you need a vaccine if you've already had COVID-19?
43:37 New vaccine approvals and vaccine efficacy

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[JAMANetwork]

Topics discussed in this interview:
0:00 Welcome Peter Piot, MD, PhD
1:22 Reflecting on the pandemic and its surprises
4:20 Asymptomatic spread
6:49 Missed opportunity regarding masks?
8:19 Masks and reductions in flu reports
8:38 New variants and the vaccines
14:18 Should vaccine efforts target something other than the S protein?
17:16 New COVID-19 variant concerns
18:30 Single dose vaccine concerns
21:58 Vaccine rollouts in the UK
23:34 Current progress on treatments for COVID-19
29:41 Being a "long Hauler" with persistent symptoms
36:00 Addressing vaccine inequity
40:20 Have you been vaccinated?
41:29 Do you need a vaccine if you've already had COVID-19?
43:37 New vaccine approvals and vaccine efficacy

[pebblelucas]

Thank you so much for sharing this valuable information. I am a case investigator for COVID-19.

[Reginaemss]

What a fabulous interview and dialogue with Peter Piot you so much for sharing your knowledge, wisdom and experience.

[timjordan]

Thank you! This was very helpful and informative. I share your podcasts with my public health students at the University of Toledo.

[lilylevental]

Thank you for sharing knowledge and personal experiences. I totally agreed to the global approach and people should be center of when dealing with COVID19. Fixing public health will fix the economy

[badalyanarman]

Valuable comments, especially related to the last question. Thanks.

[styleexnietz]

the authentic individual, scientist and explorer in our century. Thanks Peter.

[sandeepautpat]

“Best is the enemy of good”
Never heard it used it in such a context - So Apt
Thank you for your candor, Dr Piot

[juancarloslopez-corbalan]

Min 7:48 the "Spanish flu" was originated in USA, DURING WWI.

[nxjitki]

Intelligent informed discussion. Thanks for educating, sharing with the interested.

[schleidernatanlmd]

Terrific informative interview, thank you Dr.Bauchner and Dr.Pilot. Has anyone seen this vaccine information in the 'reputable' media or a Vaccine Information Sheet to provide patients?

[sandeepautpat]

👏👏 Dr Bauchner and the interviews he conducts. Each one of them is so informative and interesting. Keep up the good work JAMA

[seshpabsty]

In depth Q & A session << very informative and an eye opener in reference to variants or mutants and the needed preparedness. Candid discussion of serious underlying issues. 👌👏🏻🙏🏻

[junepagan]

Very insightful, thank you very much! Be well!

[marionpettkus]

I am 1000% AGREE with all you say...I have literally pull my hair out since January. It's just unbelievable how hard it is to have high paying individual and institutions doing the right thing. Nevermind regular people. I can't believe that Testing was the subject...Asia is doing so much better. If we don't get people be able to test with or without SYMPTOMS. I really don't get it....on one side they say Testing is important...on the other side the questions disqualify you.

[lilysunshine]

Other than respiratory system what forms of transmission occurred to make it pandemic?

[kayakutah]

Regarding mRNA vaccines:
My limited understanding is that the mRNA causes the spike protein to manifest on the surface of human cells and this activates the immune system. Does the spike protein manifest as a structure on the human cell, and if so, is there a risk of autoimmune reactions where antibodies attack the human cells which have this protein structure? Or, does the protein structure "break off" of the cell surface, circulate, and by that means cause an immune response that does not involve the cells themselves?

[joanhyde]

Thank you for sharing tour wisdom and experience, Dr. Pilot.

[Machster]

The virus can be shut down in four weeks if everyone wore N95s.

[lilysunshine]

What was the environmental history where virus originated? Would that give clues of series of mutations from all other ecological research