Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine

In this episode, Dr. Michael Snyder discusses the future of personalized medicine through the use of wearable technology and big data.

Dr. Michael Snyder, the chairman of the Department of Genetics and director of the Center for Genomics and Personalized Medicine at Stanford University, is a pioneer and powerful advocate of "deep profiling." Deep profiling seeks to apply intelligent analysis to large data sets to yield specialized clinical insight, ranging from common consumer-grade wearables like Apple Watches to whole-body MRI, continuous glucose monitoring, and metabolomics. The proud bearer of eight wearables, Dr. Snyder describes himself as one of the most extensively monitored scientific researchers, a firm believer that "more is better" when it comes to data. #wearables #CGM #personalizedmedicine

EPISODE LINKS:

PODCAST INFO:

Chapters:
00:00:00 - Introduction
00:02:36 - Surprising diabetes diagnosis
00:08:59 - Continuous glucose monitors
00:16:52 - Creating deep profiles
00:27:12 - Detecting disease w/ wearables
00:35:22 - Heart rate variability
00:36:49 - Airborne pollution
00:47:12 - Discovering ageotypes
00:54:13 - Exercise benefits
00:59:19 - His personal habits
01:01:47 - Improving microbiome

SCIENCE OF HEALTHSPAN EMAIL NEWSLETTER:

SUPPORT THE CHANNEL:

Thank you for watching!

SOCIALS:

PODCAST:

Free metabolism SNP report for consumer genetic data:

[jsmitha]

Dad of a T1D kid here. CGMs are amazing, I can't imagine life without one and my kid has been wearing one (Dexcom G6) since they were diagnosed with T1D at 4. It's what allows us to maintain a close to normal HbA1C (~5.8). I'd love to try one out and may ask about one this year at my physical. What they say about different foods effecting each person differently is true. My kid reacts differently to foods than many others do, and each T1D tends to find what foods spike them and which don't. Exercise is also amazing...running around playing can drop my kiddo through the floor in minutes if they have a bolus on board. Vigorous exercise (swimming, hiking, etc.) requires us to turn basal off or have high carb snacks on hand.

Anyone who CAN get a CGM should try one out. Dexcom is awesome, but expensive. For T1Ds, they're life changing and life saving.

[ModernHealthspan]

Thanks for the great interview! We have a chance to talk to Dr. Snyder earlier where he discussed about using fitness tracker to early detect disease. We found it very useful, especially my wife have food allergy. We normally wear the fitness watch only during exercises. Now, she wears the fitness watch before and after meals. Her normal heart rate is around 50, she can see her heart rate jump up to 80-120 after she had food that trigger her allergy even she just sitting down. So, based on that she can make better decision to avoid the food that is not good for her. It's very effective and don't cost us extra money. We are so grateful to have talk to Dr. Snyder.

[chrismartin]

I have a Freestyle Libre 2 with Ambrosia Systems BluCon transmitter. I paid for this w/o insurance support. The results of my experiment are AMAZING! CBGM should be available for EVERYONE for free via insurance. It is insane that our health system doesn't provide systems that promote HEALTH care. Instead, we spend (collectively) billions on T2D care.

[jonasion]

What a great interview, and I might add that the text blurbs, quotes and helpful information at the bottom makes me spend 40% more on watching the video. It is VERY helpful to get a better understanding in-real time, almost, of a subject matter that's being discussed. Have not seen this before on other vids, and wanted to let you know that THIS is why I subscribe, and why content is of such high quality. Absolute gem.

[cryingturtle]

I could listen to you talk for hours.... Oh wait I do.
Thank you for sharing the knowledge

[ifoundthistoday]

David Sinclair on the lastest Lex Fridman podcast spoke a lot about these CGM devises and said he's working on a very inexpensive version right now

[John-hjed]

Dr. Patrick - Intense, bright, and always ahead of the game (especially hosting leading edge scientists)

[MushiroMushroom_hai]

I think the biggest problem moving forward with this is going to be cost. Most people can’t afford this type of monitoring and testing. Insurance certainly won’t cover it.

Snyder hit the nail on the head. Companies make money from illness, not health.
This is so amazing. I would love to sign up to be measured and monitored.

[AJ]

Dr. Rhonda, this is an important interview as it reveals the future of health medicine -- and because it provides such valuable information. I appreciate the extra work you do to insert the journal citations and other data. Your questions were excellent as well. And I enjoyed the long un-interrupted segments where he could talk freely. And you look so pretty.

[davidleong]

I always appreciate Dr. Rhonda’s definitions and notes she thoughtfully provides on the bottom of the screen allowing us to gain a greater understanding of the subject in proper context.

[BodyworksPrime]

My second time listening to this in its entirety. I really like the question: "If you can't measure it then how do you know something is improving?". I think that's something we should ask ourselves in everything were trying to improve, even outside of own body's health. One of the key principles of SMART goals is that the goal is measurable!

[TheSheekeyScienceShow]

The concept of ageotypes is great and will definitely help us strive towards personalised medicine. Super cool interview!

[rickfucci]

I heard Dr Snyder back in 2012. He was sorta the first academic that seemed to be working on a comprehensive scientific approach to health. Glad to see he is still on the path. Great to be able to check in on his work. Thanks..

He had predicted it would cost about $2500, looks like he didn't miss by much at $3500. How many measurements did he end up using out of the 40, 000 they started with????

[terristewart]

Wow! So glad I found this podcast! I am using a CGM to avoid diabetes. It is such a great tool. Thank you so much for sharing all this information. It is amazing what proper nutrition, exercise, sleep & stress management can do to heal our bodies.

[Zane_Zaminsky]

Great video, Dr. Patrick. Dr. Snyder has done such great work. I watched this video and other videos that highlight his groundbreaking research. He is to be commended.

Yet I see criticism about Dr. Snyder because he didn’t know much about pulled pork!

Anyway, keep up the great work. I am a college Math/Statistics Professor and Data Scientist. I am also a new subscriber, and I am delighted with your videos and your great interviews.

[threewishes]

This episode should be in millions of views.
Incredible information 👏

[m-hadji]

Good information. I am T2D and I have CGM and it changed my view to my body response to everything e, g food, exercise …

[bartoszulkowskitattoo]

on the screen additional info is a amazing! I am watching this videos multiple times to understand it better!
Thank You so much for your hard work!

[lthaus]

I had out of control T2, but thought everything was fine.. An internal infection opened my eyes and I fought for a CGM. I went from over 400MG/dl down to under 100 in a few days and with my CGM, I'm able to see cause and effect at a real time level. It should not be this hard, but I'm also a Data guy and More is better.

[erikjarrett]

I had the same temp and resting heart rate increase when I got rocky mountain spotted fever. That helped tip me off and get doxycycline. Cleared it up VERY quickly. I felt much better overnight.