Edward Jenner contribution to microbiology I Father of Immunology

He was the first person who
successfully introduced vaccination
to prevent Smallpox.

The terms vaccine and vaccination are derived from Variolae vaccinae (cowpox), and the term devised by Jenner to denote cowpox. the Latin word for cow (vacca).
The cowpox (Variolae vaccinae) virus is closely related to variola virus, the causative virus of smallpox.
Before Vaccination discovered:

The only means of combating smallpox was a primitive form of vaccination called variolation or inoculation—intentionally infecting a healthy person with the “matter” taken from a patient sick with a mild attack of the disease.

Search for Vaccination:

Jenner had been impressed by the fact that a person who had suffered an attack of cowpox—a relatively harmless disease that could be contracted from cattle—could not take the smallpox—i.e., could not become infected whether by accidental or intentional exposure to smallpox.
Vaccination History:
In May 1796 Jenner found a young dairymaid, Sarah Nelmes, who had fresh cowpox lesions on her hand.

On May 14, using matter from Sarah’s lesions, he inoculated an eight-year-old boy, James Phipps, who had never had smallpox.

Phipps became slightly ill over the course of the next 9 days but was well on the 10th.

On July 1, Jenner inoculated the boy again, this time with smallpox matter. No disease developed; protection was complete.
In 1798 Jenner, having added further cases, published privately a slender book entitled An Inquiry into the Causes and Effects of the Variolae Vaccinae, known as the Cow Pox, in which he described the protective effect of cowpox against smallpox.

[mohiuddin]

Very helpful... ❤❤❤
Highly recommended for juniors of microbiology Department

[prachi]

Great explanation. These notes are helpful.