DNA Methylation - Biochemistry (USMLE Step 1)

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[bts_rollercosterlifepurplearmy]

After watching so many videos on this topic now I finally understand the concept...

[cheyannerainbow]

ok but this is SOLIDD for MCAT too, thank you soooo much.

[simonsteen-andersen]

Great video, - thank you! Could you make a video about the role of the p38 mapk pathway and CpG DNA methylation in immune cells? (TLR9)

[mgold]

Just for clarification, 75% of C's in CpG dinucleotides are 5mC's (methylated) which in my opinion is not the same as to say that human DNA is 75% methylated. About 1.5% of all C's are 5mC's in the human genome in somatic cells. Worth to note is also that 90% of CpG islands are unmethylated.

[westfield]

I have a stupid question but where does the body get all these raw materials such the ribose sugars and bases from? All the materials to form proteins for the hundreds of enzymes and other functional proteins that are happening all day long? How much of a meal provides the body with all of these raw materials? Suppose I ate Doritos every day as my only meal for a month would the body’s processes come to a standstill since I’m not providing protein and nutrients?