The clock in our genes and in every cell of your body | Joseph Takahashi | TEDxSMU 2013

Joseph S. Takahashi, Ph.D. is the Loyd B. Sands Distinguished Chair in Neuroscience, an Investigator of the Howard Hughes Medical Institute, and Chair of the Department of Neuroscience at the University of Texas Southwestern Medical Center in Dallas. His research interests are the molecular mechanism of circadian clocks, neuroscience, and the genetic basis of behavior. Dr. Takahashi pioneered the use of genetics in the mouse as a tool for discovery of genes underlying neurobiology and behavior. His awards include the Honma International Prize in Biological Rhythms Research in 1986, W. Alden Spencer Award in Neuroscience from Columbia University in 2001, Eduard Buchner Prize from German Society for Biochemistry and Molecular Biology in 2003 and Outstanding Scientific Achievement Award from the Sleep Research Society in 2012. He was elected a Fellow of the American Academy of Arts and Sciences in 2000, and a Member of the National Academy of Sciences in 2003. He was a co-founder of Hypnion, Inc., a biotech discovery company in Worcester, Mass., that investigated sleep/wake neurobiology and pharmaceuticals (now owned by Eli Lilly and Co.), and is a co-founder of ReSet Therapeutics, Inc., a biotech company that works on the role of clocks in metabolism.
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[hosoiarchives]

4:05 internal biological clock
8:49 gene animation, “cell clock”
11:53 SCN
14:40 chimera

[marckdan]

It's interesting how our biology is so closely tied to the natural rhythm of the earth; how all life is orchestrated by the 24hr period that makes up the full rotation of the earth around its own axis. We were, indeed, made FOR this planet, BY this planet, and made OF this planet. I have confidence alien life will not survive here. We've earned our right to exist on this rock. We've learnt to cope with the many microbial life forms that could otherwise threaten our existence. We've evolved (in symbiosis) WITH this rock, to survive & thrive it then not make all it all the more illogical that we continue to threaten, maim, and destroy this rock -- not for survival, but for greed that does nothing to prolong our transcient individual existences?

[sourbhrankawat]

I'm working in circadian biology field and I feel sad about Sir Takahashi he was close to getting the Nobel prize for his discoveries of clock mechanism in mice eventually the Nobel award was given to a fly chronobiologist.

[tube-nwrz]

3:40 여전히 일주기 리듬과 동기화 되어 있다 - 생체시계의 위치
6:17 쥐에게 일주기 리듬이 있다는 것이 밝혀짐
8:54 일주기 리듬은 어떻게 움직이나요? 애니메이션

[walterscott]

Can't hear. Volume is too low to be able to follow comfortably.

[DiesleWhite]

Had they not figured out you can't "catch up on sleep" 10yrs ago?

[riteshmahajan]

just to hear the last four words, I watched this whole talk

[Atravick]

So how do the master clock cells in the brain interact with all the other cells in our body?

[vasantipunchoo]

Volume low. Wish cd have the text to read

[Acidoverwrite]

What type of Lights energy do we use to regenerate?

[geofffeltham]

Sell Human Centric and this was a fantastic presentation. I thought I knew a lot before but this elevated my knowledge to a new level.