D.8.1 Geometric isomers in metal complexes and biological activity IB Chemistry HL

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Alkenes and cycloalkane based geometric isomerism is not the whole story. Complex ions can also exhibit this type of isomerism and this can have biological implications. For example cis-platin ,[Pt(Cl)2(NH3)2] is an anticancer drug that causes DNA damage to cancer cells and then apoptosis (programmed cell death) of these cells. The trans version of the drug has no anti cancer properties and is toxic.
  1. Richard Thornley
  2. cis
  3. platin
  4. trans
  5. geometric
  6. isomerism
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Thakn you so much for your videos! I'm actually forgetting that I'm reviewing for the exams... It's actually pretty fun!

nawedy
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it's 4 AM, my paper 3 is in 5 hours. I officially give up. Thank you for all your help, without you I wouldn't be able to answer the few questions I can!!

SophiaBaba
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For me. I write time zone 1. And is 12 at night. Paper is in 9 hours.
Thank you Richard so much. Ur my life saver on paper I. Should have studied acid and base a bit better for P2. so many of them

andi
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Hi Richard!
Which software are you using for your illustration of molecules etc.?

erikoscarsson
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Christ - get to bed love - and dream of Dr Atkinson, Florey, Chain and me babbling in these videos.

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