Lentiviruses: A Versatile Tool for Cell Biology Research

- Cell-based experiments are a cornerstone of life science projects, particularly in the pre-clinical research fields of target validation and drug discovery and development. The ability to manipulate the cell genome, induce the expression of a particular protein, or accurately and reproducibly quantify the activity of antibodies and small molecules using reporter systems has considerably accelerated the pace of scientific progress. In this respect, lentiviral vectors have become essential gene delivery tools as they stably infect a large variety of dividing or non-dividing cell types in a wide range of hosts, leading to high efficiency of transduction. Pseudotyped lentiviruses are not only versatile, they are also safe and need only BSL-2 as opposed to BSL-3 containment practices. BPS Bioscience offers a comprehensive—and growing—collection of lentivirus-based particles, cell lines, and reporter systems, including a substantial list of COVID-19 related research products and CRISPR/Cas9 cells.

This webinar will present an overview of:

- Advantages of ready-to-use lentiviral particles
- Types of lentiviruses and their roles
- Lentivirus-based products
- Application examples in cell culture
- Tools to study SARS-CoV-2 variants