Clearance & Half-Life - The Pharmacokinetics Series

You're halfway through! This video explains the concept of clearance and half life. It is recommended that you watch this video before you watch the ones on metabolism and excretion.

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[palshah]

My God why has this channel not taken off yet ??!!

[amalalhassun]

Im really suffering from pharmacokinetics. Im very grateful for your videos, simple and direct . Thank you

[sunrunnernge]

A clear well explained video! Highly recommended and subscribed !

[amalalhassun]

Please continue uploading videos like these

[karlint]

I'm not a pharmacist, but I found this video fascinating. I have heard about the half life of drugs before -- hence some drugs work very quickly while others take a long time to build up over time and therefore take longer to start working. But I recently became aware that the same principle applies to the protein albumin. So I suppose that a person consumes protein, the liver then synthesizes albumin, and through the body's various processes the albumin gets used up and this can be tracked with a similar kind of half-life. If the model you described applies to albumin, it would be very interesting to know more about that. Thanks again for making this helpful video

[mutiakartikasani]

This video really helps me understand!! Thank youu💕💕

[JayLivesInJames]

Thank you for your series of videos! You're doing a great job for FOMEd!

[fxseh]

Thank you so much! very well done, I finally got it!

[shahad]

You are a life savior thank you so much ☹️❤️

[k.t.]

Not a doctor but great job I could comprehend everything

[pratibhasubedi]

How is the 50% clearance of liver and 50% clearance of kidney develops renal failure?

[TinoPetersson]

Important note:
At 0:31 you say that "Metabolism in which the drug is transformed into an inactive substance (...)"
This is only true for most Phase II metabolic reactions.

Phase I metabolic reactions do not inactivate the substance - often Phase I metabolism is used to convert prodrugs into active drugs.

So this is an extremely dangerous generalization to make 30 seconds into the video. Otherwise thank you for a great series.

[Psalmsful]

Is this the same as elimination half life ?

[asimrph]

can you please tell me which software do you use for making your animated videos.
Am really thankful if you reply.
Thanks.❤️