Lecture 9b: Autoimmunity

UCSD Extension School: Applied Immunology (BIOL-40371)
Spring Quarter 2021
This lecture covers autoimmune diseases, a group of pathologies where inflammatory immune responses are inappropriately used against self antigens, leading to immune attack of otherwise healthy tissue. It discusses the mechanisms of central and peripheral tolerance and how they may be broken by both genetic and environmental factors in autoimmune disorders. It also presents a summary of mechanisms for myasthenia gravis, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), type 1 diabetes mellitus (T1D), and multiple sclerosis (MS).

All figures are either from Janeway's Immunobiology (9th ed.) or other publications where noted, or my own original figures.

[tungohoangviet]

Ma'am, your immunology course is truly amazing with both comprehensive and in-depth knowledge! Could you please make some courses about cell biology and cancer biology, Ma'am? Wishing you a happy and healthy 2022! Love you, Prof. Snyder. I have read some of your papers and I have to say that the way you write and express ideas are so easy to understand for a student like me! Please take great care, Prof. Snyder! I wish you all the best!

[hussenmohammed]

doctor Snyder, I'm so grateful to you for this comprehensive course, but I wish to learn about immune response and cascade reactions of it at both cell & humoral mediated immunity in more details .