Hypersensitivity Reactions Type 3 | Part 1

#type3 #hypersensitivity #immuneresponse
#classification #GeneralisedReactions #SystemicReactions #SerumSickness #AplasticAnaemia
#ClinicalPresentation #patientmanagement #atgshorts #reactions #fundamentals  #immunesystem #rheumatoidarthritis #SystemicLupusErythematosus #PolyarteritisNodosa #PostStreptococcalGlomerulonephritis #SerumSickness #ArthusReaction #FarmersLung #HypersensitivityPneumonitis #ChronicHypersensitivityPneumonitis #SjögrensSyndrome #MixedCryoglobulinemia #ReactiveArthritis #sarcoidosis #SubacuteBacterialEndocarditis #ChronicActiveHepatitis

Hypersensitivity Reactions Type 3 | Part 1

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

00:00:00 Basic fundamentals of Type III Hypersensitivity Reactions
00:04:10 Classification of Type III Hypersensitivity Reactions
00:05:00 Overview of Generalized/Systematic Reactions
00:05:29 What are serum sickness-like reactions?
00:06:46 Clinical presentation of a patient with Aplastic Anemia
00:17:49 What are the key considerations in managing patients with aplastic anemia?
00:22:17 How do Serum Sickness/Type III Hypersensitivity reactions occur?
00:23:53 How do ATGs trigger serum sickness-like reactions or Type III hypersensitivity reactions, and what is the detailed process behind the formation and deposition of immune complexes?

Type III hypersensitivity, in the Gell and Coombs classification of allergic reactions, occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. There are three steps that lead to this response.[1] The first step is immune complex formation, which involves the binding of antigens to antibodies to form mobile immune complexes. The second step is immune complex deposition, during which the complexes leave the plasma and are deposited into tissues. Finally, the third step is the inflammatory reaction, during which the classical pathway is activated and macrophages and neutrophils are recruited to the affected tissues. Such reactions may progress to immune complex diseases.
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[evgeniychupakhin]

Thank you Doc from Russia, I am biochemist and your lecture very important for my students

[DrowningAndjustdrown-nhwq]

Where is the 2nd part, plz add it as soon as possible
And please add type 4 also that will be your kindness

[SSCWalah]

Sir thank you so much for lecture series