Basics of Sequence Alignment #Sequence_Alignment #Bioinformatics #DynamicProgramming

Comparative genomics and genome sequencing allows comparison of organisms at DNA and protein levels, and sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.
The sequence Comparisons can be used to
- Find evolutionary relationships between organisms
- Identify functionally conserved sequences
- Identify corresponding genes in human and model
- organisms: develop models for human diseases
Therefore, sequence alignment is an important first step toward structural and functional analysis of newly determined sequences to draw functional and evolutionary inference.
In this tutorial we are going to learn about the basics of sequence alignment, and it answers few of the commonly asked questions about sequence alignment. Questions that are addressed in this tutorial includes:
1. Why sequence alignment is performed?
2. What are Global and Local Alignment?
3. How dynamic programming helps in obtaining the optimum alignment, between two sequences?

[richanarayan]

thank you for simplifying everything. pls do make more bioinformatics video .. the explanation is so understandable.

[shhmaxi]

Great video, really helpful, i just find the music slighlty perplexing since it makes it harder for me to follow your talk. just take that as a feedbeack
genereally really appreciate your effort!!

[Reeltonic]

Thank you so much sir, really well explained 😊

[naqeebraja]

Can you tell me the refrence from which you collected this data?

[ricodsanchez]

hello sir, your video helped a lot. please can you make another video on this or give me the names of books that will help.

also if one finds a difference between 2 sequences. what would one do with this information?

kind regards

[amanrajput]

just know that you’re very terrible at explaining such dry course thanks