Essential Thrombocytosis (ET) | Myeloproliferative Neoplasm (JAK2 Kinase)

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Essential thrombocytosis is one of the myeloproliferative disorders.
All cell lines are increased especially platelets.

Books that I use for this series:

[younghwankim]

"If you haven't subscribed, there is no hope for you" LMAO

[MedicosisPerfectionalis]

Please, help me reach 35, 000 subscribers and I will start uploading videos on “bleeding and coagulation disorders” instantaneously.
Thanks 🙏

[aremedyproject]

Love your channel still lol. And I’m not even a med student. Your humour and honesty compliment pathology really well and help make medicine meaningful. Thanks!😊👍🇨🇦

[hx]

so glad i found your channel....my hemato module is saved!

[rapharenthlei]

Your videos are so helpful. Please! don't stop doing the amazing work. ❤️

[musallamlama]

Hi
Please note in the case study the last option was >20% myeloblasts .. your interpretation was CML.. that is not the case, i think you meant AML
.. thanks for your nice useful videos

[danagreenberg]

if im gonna pass my tmrws hematology exam its thanks to u

[roboodonnell]

Thanks for producing a very informative video. You are appreciated.

[AzulCelestex]

My exam is the next week so you save, thanks!

[olivierplayer]

my mother has double of normal platelets counts and had jack 2 mutation, after had operation at carotid and the day after had big stroke in brain .now is completely paralized for 1 year already .why did they operate carotid when they knew she had to much platelets just before operation ? they had to remove exess platelets before operation but didnt do that , why ???

[chanelfitzgerald]

I got ET when I was 32, am now 43. It is now becoming common in children as well. Very interesting that you show little symptoms until about 40 and then haematologists start with medications. Luckily I am on aspirin but I do definitely notice a change in symptoms. You almost feel like a fraud when you first get it as you don't have any visible symptoms except high platelets and tiredness. Took me a long while to get to grips with mentally.

[pokermel]

Hmm you didn't include anything about the CALR mutation that is found in ET patients.

[jacobjasch]

Im a 23 year old male and I've been diagnosed with Essential Thrombocythemia. I'm JAK2 negative, but CALR GENE is present. I had a good laugh when you said it's a disease of the elderly and more common in women since I'm a young man 🤣🤣🤣🤣

[krishnapriyasamaleti]

Why INF - alpha is given in PCV or ET?
And could you pls 🙏🙏🙏make videos on cardiology also it would be really helpful ☺☺

[aggiestarza]

I (F45, now) was diagnosed with ET @29yo, jak+ and feel like there’s nothing there for people like me. It’s all about old people and nothing for younger patients like myself. Medical professionals don’t know what to do with me. I’m not healing well and I was told it’s because I’m aging and I’m basically old and therefore nothing to do with my et. I’m in a process of changing my medical team as I’ve been gaslit by this clinic way too many times and above is just one example. Also medication to treat et cause to many side effects for younger patients to function at full capacity but I’m forced to work full time and all my complaints about any side effects from any of the meds above (and I was on all of them already), are treated as I’m saying lies. Doctors don’t know how to help me effectively so I can live my life and stop comparing me to their elderly day to day patients.

[aliciaoliver]

I am going to comment hope I get an answer...I have had high platelets and high wbc since 2010, two bone marrow biopsies showing same as blood work anemia. I have recently had some problems namely the H-pylori bacteria hopefully after treatment and recheck it will be gone, but I am still being sent back to hematologist oncologist he already did bloodwork everything came back except for the JAK2 could the H-pylori been causing the high platelets and high wbc all these years????

[kayteapod]

I don't know if I would classify it as something only the elderly are diagnosed with. I'm 27 and was diagnosed a couple months ago, and I am in a couple FB groups that have a good amount of young people in there. I think due to the improvement in technology, maybe we are able to diagnose sooner? I'm no expert, of course, and I am still learning a lot about this disease.

[mio]

Still watching in 2024…for my exams😂 Live savior ❤

[drsahiba]

Why increase in platelets leads to increased risk of bleeding?

[yasseral-ghabra]

thanks. can you explain about topics in surgery ?