Journal Club | Monitoring Refractive Development in Mice to Investigate Mechanisms of Myopia

Refractive development is a complex process that involves aligning the eye’s size with its optical power. When this process fails, refractive errors and blurred vision occur. The prevalence of myopia, the most common refractive error, is rapidly increasing worldwide, posing a significant public health concern. Extensive efforts are currently underway to understand the mechanisms behind myopia development to improve prevention strategies. Monitoring refractive error in animal models using an automated Photorefractor has enabled detailed investigations into these mechanisms and has been invaluable in this pursuit.

In his presentation, Reece will share data from several recent studies that utilize automated Photorefractor technology to explore how various environmental, pharmacological, and genetic manipulations in mouse models influence refractive development and myopia progression.