Huntington's Disease | Pathology of Huntington's Chorea | Diagnosis of Huntington's disease

In this video, we will talk about Huntington's Disease, pathology of Huntington's Chorea and diagnosis of Huntington's disease.

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0:00 Introduction
0:41 Highlights
1:26 Movement disorders In Huntington's disease
2:07 Impaired gait, posture, and balance in Huntington's disease
2:41 Progression of Huntington's disease
3:24 Initially, damage to the brain is regionally specific with the dorsal striatum in the subcortical basal ganglia being primarily affected.
5:33 Geographic distribution of Huntington's disease
6:01 Genetic basis of Huntington's disease
6:39 Diagnosis of
6:49 Genetic counseling for
7:11 Life expectancy for Huntington's disease
7:29 Treatment for Huntington's disease
8:18 Revising is easy with dynamic flashcards

[mahalekshmim]

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I am Mahalekshmi a MBBS student from kottayam medical college I usually watch your videos for the reference and it helped me a lot....
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[BabuluResearcher]

Hi, Arpan; lovely representation. I want to add some new lines. There is evidence that Huntington aggregates also affect muscle health. It is not restricted to neurons. Muscle Huntington aggregates can affect motor activity that's what evidence say (though these are looked poorly). Also, the aggregates are found in muscle cells. Muscle Huntington aggregates affect homeostatic synaptic plasticity. These can be rescued by expressing specific heat shock proteins. I have worked with various repeats and tested many chaperones, which I am not disclosing here as these are under communication. Major part of my postdoc work is understanding muscle Huntington disease.

[maryamlahlou]

Hi! Thank you for this video :) Could you please provide the sources for the information discussed?

[assmaalani-tv]

Very beautiful and successful especially explaination on pictures
My favorite way 🙏

[hussamadam]

summarized and informative .thank you for your effort .

[shawnmulberry]

My grandfather had Huntington's. I recall the day I was filling his cup of coffee and he said, "only half a cup". I thought it was because too much caffeine bothered him but he said no. He picks up his cup and it swings back and forth. He then said, "if you pour me more than half a cup I still only get half a cup". It was weird to watch because it would stop swinging by the time he got the cup to his lips. He did not show signs until his late 60s and then he had a stroke at 76 and died at 78. He never seemed to be depressed or lacking cognition until maybe after his stroke. He did not seem to be deeply afflicted. I suppose I should get my DNA checked for the presence of the gene(s).

[dr.monitha]

Hi. My Mother in law was diagnosed with HD chorea eight years back. She suffered a lot and we lost her about a year back. My husband is now 36 years old. He recently found that he is facing focus issues in his work. So we thought of getting a genome test for the HD through MEDGENOME LABS, BENAGULU.

sadly the result came positive it's been a couple of weeks since the result, still trying to cope up. We have an 8 year old daughter and we worry about her a lot.

In India awareness about HD disease is null. Hope some work is done in the coming future.

[kritikaroy]

My dad had it. There is so less awareness regarding this in India yet so many are suffering. So many neurological doctors also dont know about this disease. It was heartbreaking to see father in so much pain and now i want to get genetic testing. But cant find any genuine lab which will do the testing. If any one knows kindly guide me. Thanks❤

[meenashah]

In my family fifth generation started huntingeon disease what to do stop this disease

[Bankura]

My mother had it, and we are two sisters, now at the age of 26, and 28, and thinking about not to marry anyone, not want to spread this hd to our generation. Its very pathetic..

[ShubFood]

I have my mom video, she have had chorea 24hrs 60 sec full body vibration, i don't want to upload that