Coordinated Alternative Splicing and Alternative Polyadenylation | Pedro Miura, PhD

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The lab of Pedro Miura studies two types of RNAs- long 3´ UTR isoforms and circRNAs. Thousands of these RNAs exist in the brains of many organisms, including humans. One focus of the group is to uncover functions for such transcripts in the nervous system. The group uses mouse and Drosophila as model organisms, and employs high-throughput sequencing and CRISPR genome editing in our research.

This talk was given as part of Devoted to Heart Development: Bruneau 20th Anniversary Symposium which was held on March 19, 2021 via Zoom.
  1. Gladstone Institutes
  2. Science
  3. Research
  4. Stem Cell
  5. Cardiac
  6. Neuro
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Комментарии
Автор

Hello professor, I am curious about something.
Polyadenylation protects the mRNA from the degradation from phosphatases and nucleases and is necessary for export of mRNA from the nucleus into the cytosol.

Sir, why it's only poly A tail ? Why not poly G tail or poly C tail ?
Why only adenine is used ? If say it was poly G tail wouldn't it have the same effect on stability?

ishapandey
Автор

How to obtain diagram like 7:15? I also wanted to create one

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