Why is knowing your free light chain ratio important?

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[Willow]

Simplistic, yet very specific and easily understood explanation. Packed with all the important details of inflammation, CKD and Myeloma. Thank you so much!!

[leannshort]

Thank you for this! I was scared when I saw my Kappa and Lambda were elevated. Kappa is higher than the Lambda like you explained. But ratio is within range at 1.60… Thank you for this. Now I’m not scared! Just another confirmation of the inflammation going on in my body.

[tracyt]

Wheew thank you for such a clear clarification on these cell test and numbers...

[masteronionnorth]

I had some recent blood work done
Via my allergist.

Some of the results were abnormal...

My free kappa was 17.11
Normal range is 3.30-19.40

My free kappa/lambda is 1.54
Normal range is 0.26-1.65

My free lambda is 17.62
Normal range is 5.71-26.30

Additionally: other abnormal results:

My Abs CD3+ (blood) is 0.657
Normal range is 0.856-2.669

My Abs CD4+ CD4 (blood) is 0.413
Normal range is 0.491- 1.734

Abs lymphocytes is 0.980
Normal range is 1.000-3.200

My Abs lymphocytes flow (blood) is 1.052
Normal range is 1.500-2.900

My IgA is 4.38
Normal range is 0.66-4.33

I have a history of weird symptoms. I've also had sustained elevated IgA levels for years now. Doctors are unable explain this.

[umibrahimibrahim]

The best explanation.. I looked hard for it.❤

[TheRykpaalt]

Great presentation! Thank you so much!

[msocr]

Husband diagnosed 2023 with MM. kappa/lambda ratio was 54.10.

[GoldenBreeze]

My recent few labs show the last scenario Kappa rising, lambda dropping, and K/L ratio rising but I don't know if it's enough to be more than still just MGUS yet. We have been watching it for 11 years.

[johnsontimbal]

i had high kappa light chain free 25 what is that means?

[marandabest]

So why would the light chains to be normal and the ratio to be high?

[maxwilcox]

what genes are these kappa and lamda chains from?

[nolimitsshan]

My body is literally attacking itself. I've been diagnosed with MCAS. Im in pain almost everyday. Constant nausea, fatigue, muscles weakness and tenderness, joint pains, neuropathic pains and chest pain. Doctors still dont have a clue whats wrong with me. Hopefully I get some kind of relief soon.

[Emily-yvqu]

Mine is 0.00 0.03 kappa lambda ratio and I am in so much pain

[diegorivera]

Hello.. how the total light chains relate to the free light chains tests in detecting MM?
And How far can this ratio be to say it is MM?

[easystudy]

IgA 597 mg/dl
IgG 644 mg/gl
IgM 35 mg/dl
Total light chain kappa 151mg/dl
Total light chain lambda 157 mg/dl
Ration = 0.96


Can someone explain this, am i on remission or not?

[GD-crum]

I'm a caregiver for a myeloma patient and his kappa is 569 he was told to do chemotherapy and the side effects of chemotherapy also cause infection. Our medical system is flawed

[sunshinelovenv]

i have monoclonol gamathies. They send me those test. I have never fully understand this. If the doctor says the bloods are ok, From 3 doctors say the same thing. So I just dont worry.

[garlandowls]

Okay. I have a question! My mother's Kappa light chain and Lambda ligh chain are both extremely high. Does this mean multiple myleoma?

[kathleenkoval]

?kappa/lambda ratio 0.20 ? Free Lambda LT chains 75.13