Functional Roles of the Novel Membrane Associated AAV Protein MAAP

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Presented By: Lionel Galibert, Ph.D.

Speaker Biography: Dr. Lionel Galibert has accumulated over 15 years of experience in the adeno-associated virus (AAV) gene therapy field. On the team of Dr. Otto Wilhelm Merten in Genethon, France, he helped develop a single baculovirus to produce rAAV8 in Sf9 cells, as well as demonstrated the involvement of the baculovirus protease on the degradation of certain AAV capsids.

Webinar: Functional Roles of the Novel Membrane-Associated AAV Protein MAAP

Webinar Abstract: The adeno-associated virus (AAV) has evolved overlapping genes to maximize its genome use, as with the recently-discovered ORF in the cap gene which encodes a membrane-associated accessory protein (MAAP) located in the same genomic region as the VP1/2 unique domain. This 13 KDa protein, unique to the dependovirus genus, is not homologous to any known protein.

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