Trialing Outpatient Treatments for Moderate COVID Cases | COVID-19 Media Briefing

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A new study led by the Duke Clinical Research Institute is looking at whether three existing medications would treat mild-to-moderate COVID-19 effectively. (More information on the study is available here.)

The three repurposed medications, already approved by the U.S. Food and Drug Administration for other uses, are:

- Ivermectin, used to treat parasitic infections;
- Fluticasone, an inhaled steroid commonly prescribed for asthma and chronic obstructive pulmonary disease; and
- Fluvoxamine, a selective serotonin reuptake inhibitor (SSRI), often prescribed for depression.

On Tuesday, institute executive director Adrian Hernandez discussed the study with reporters in a virtual media briefing, where he touched on the need for COVID-19 therapies and making it easy for people across the country to take part in the study.


𝐓𝐡𝐞 𝐏𝐚𝐧𝐞𝐥𝐢𝐬𝐭

Adrian Hernandez, M.D., is a cardiologist, vice dean of the Duke University School of Medicine and executive director of the Duke Clinical Research Institute, where he oversees clinical research programs, clinical trials and clinical education.

𝐌𝐞𝐝𝐢𝐚 𝐁𝐫𝐢𝐞𝐟𝐢𝐧𝐠𝐬
This video is part of a series of media briefings where Duke experts speak on current issues.

𝐀𝐛𝐨𝐮𝐭 𝐃𝐮𝐤𝐞 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
A private research university located in Durham, North Carolina, Duke University is known as one of the world’s leading institutions for education, research, and patient care.

𝐅𝐨𝐥𝐥𝐨𝐰 #𝐃𝐮𝐤𝐞𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
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I'm very happy to see this nationwide trial for early treatment of Covid. I'm only sorry that it took so long. We should have done this in 2020.

pmorlan
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So glad to hear this. I am taking the "I" drug currently with absolutely no side effects. Thank you for taking this forward.

drendaparfitt
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These trials should have been done a year ago.

terjeoseberg
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Imagine Doctor telling you " your ECG looks abnormal, but just go home and if you develop chest pains go ER." Idiots

guambroker
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Clap clap. 18 months to work out that ‘Congratulations you’re positive, go home’ doesn’t seem to be the best strategy to reduce hospitalization and death.

wisdomlistens
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Please comment on the work of the FLCCC, Dr. Pierre Kory’s group.

jamescusack
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They are dragging this out as long as possible that way they can keep pushing the jab as long as possible.

RestoreJustice
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These drugs he mentioned they've been using in India for a year now and being having quite a bit of success

peterjenner
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Better late than never I guess for those who didn’t die already due to lack of focus on early treatment.

chelseamorris
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How can you ethically send placebo to a sick person during a pandemic? How does that work?

bigears
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How about you look at the FLCCC protocol. There's more to it than just ivm - there's quite a number of parts involved, and if you only include ivm, I suspect your study is designed to fail.

zodberg
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Welcome to the party duke university. I wonder how long before your deactivated 6.

doniewa
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What drugs are you using for the prevention of blood clotting?

sandraschmitt
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If you're talking about early treatment and you're asking someone to contact you with covid diagnosis....you're already wasting quite a few days. how long before they can receive your treatment? it's a nice effort but already from the start...it can be faulty because of time wasted before treatment. Canada did the same thing....and it was doomed for failure because people weren't getting treatment until patients were already recovering and/or covid already caused hospitalization and at that point it's a whole different protocol.

GGbots
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I applaud you for undertaking this study. I'm not sure why the answers on potential treatments haven't been answered already. Seems like a pretty glaring failure of our healthcare system but at least you are trying to find the answers now.

wishiwasinidaho
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effective combo: ivermectin high dose0.5mg/kg, Artemisinin 300mg ( WHO now conducting trial artesenuate derivative of attemisinin in IV form), Nigella sativa, Zinc, Azithromycin or Moxifloxacin, and FenoFibrate 200mg

ardelbinoya
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At TWiV 659 at min29 Christian Drosten indicate low temperature better to fit SARS COV2 replication
Theoreticaly high body temperature are protecting from viral replication in SARS COV2 infection
Avoiding antypiretics and cold oxigen (by warming medical oxigen) mitigate infection
But also high blood temperature by avoiding hipotermia, can theoreticaly avoid erytrocyte agregation induced by high antinucleocapside IgM antibody

traiandanciu
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Ivermectin is possibly a good preventative, so I hope it gets studied more for this. Many are exposed to people at high risk of succumbing to the disease if they were to get it. That’s why studying prevention and ivermectin is Really Important!

amythompson
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Am I the only one who thinks this approach immoral, at a time when there are many positive results from trials into #ivermectin #Fluvoxamine and #monichlonalantibodies ?
Giving participants a placebo at this time

naomiklahn
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Is this another trial designed to fail regarding ivermectin?

cathyscott