The 2 Major Types of Medications for ADHD For Adults (Methylphenidate vs. Amphetamines)

In the video discussing the disparities between methylphenidate and amphetamine for treating ADHD in adults, viewers gain insight into how methylphenidate compares to amphetamine in addressing ADHD for adults.

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In the comparison of methylphenidate and amphetamine, the two primary stimulant medications for ADHD in adults, the video meticulously breaks down their mechanisms of action. It highlights how methylphenidate blocks dopamine and norepinephrine reuptake, while amphetamines act as pseudo substrates, increasing neurotransmitter levels in the synapse. Amphetamines generally have a better effect size, with 40% of patients responding well to both, 28% favoring amphetamines, and 15% favoring methylphenidate. However, methylphenidate tends to be better tolerated in kids, while amphetamines are more acceptable for adults despite a higher risk of side effects like mania and psychosis. Methylphenidate might perform better with comorbidities and possibly offers better neuroprotection. Overall, methylphenidate is considered safer with less abuse potential, though it may be slightly less effective, making it a preferred starting medication. The video aims to simplify understanding the differences between these medications to help patients and healthcare professionals make informed treatment decisions for ADHD in adults.

Understanding the differences between stimulants, including methylphenidates and amphetamines, is crucial in the treatment of ADHD, especially in adults. Stimulant medications such as Ritalin, Concerta, Adderall, Vyvanse, Dexedrine, Focalin, and Strattera are commonly prescribed to manage ADHD symptoms. Methylphenidate-based drugs like Ritalin and Concerta work by increasing the levels of dopamine and norepinephrine in the brain, helping to improve focus and attention. On the other hand, amphetamines such as Adderall and Dexedrine also enhance dopamine and norepinephrine activity but in a slightly different way. Understanding the nuances between methylphenidates and amphetamines allows healthcare providers to tailor treatment plans to individual patient needs, considering factors such as medication efficacy, side effects, and patient preferences.

When comparing methylphenidate to amphetamine-based medications for ADHD, it's essential to consider their mechanisms of action and potential differences in effectiveness and tolerability. Methylphenidate, found in medications like Ritalin and Concerta, primarily blocks the reuptake of dopamine and norepinephrine, thereby increasing their levels in the brain. In contrast, amphetamines such as Adderall and Vyvanse work by stimulating the release of dopamine and norepinephrine while also blocking their reuptake. These differences in pharmacology may lead to variations in how patients respond to each type of medication. Additionally, factors such as duration of action, side effect profile, and individual patient characteristics play a role in determining the most suitable treatment option. Understanding the distinctions between methylphenidate and amphetamine-based medications is essential for healthcare providers when making informed decisions about ADHD management in adults.

#adhd #adhdmedication #psychopharmacology

[tesssamoore]

no one ever includes biphentin
i only tried it for a few months and switched to vyvanse but im tryna learn

[hrdcpy]

Any hypothesis why a concussed patient would stop reacting to stimulants?

[Tommie.ManicGK]

Hey good people, I was wondering if someone could help me. My Dr recently put me on Vyvanse and I felt really Speedy and as a recovering addict it really scared me. I'm now off of Vyvanse and the Dr has switched me to Ritalin. I'm yet to start my first dose as I'm really apprehensive about how they'll make me feel. Would someone please help me to tell me if I'll feel the same as I did on Vyvanse? Thanks in advance for any guidance.

[OttomanSultana]

Are you a pharmacist or psychiatrist by training? And are you active on r/DrugNerds?

[Vince-mjlv]

Methylphenidates gave body energy, Amphetamines gave more mental energy and body calmness IMO. But the sides from Methylphenidates were way worse for me, if I took it for longer than 4 days i'd end up punching walls lol. Modafinil is awesome too just so expensive. great videos, well explained.

[pipersecretp]

Modafinil, watching from the sidelines...