Anna Kreshuk: 'Whole-organism segmentation: finding all cells in an EM-imaged platynereis dumerilii”

Anna Kreshuk, EMBL Heidelberg Group Leader.

Abstract: Cutting-edge volume electron microscopy allows to image very large samples, up to the whole animal level for small organisms. i will talk about the methods we developed to segment all cells and all cell nuclei in a volume like this, encompassing a whole 6-day old marine worm platynereis dumerilii. I will also show how - through correlation with light microscopy volumes - the segmented cells can be assigned to a gene expression profile.

Janelia’s Optical Interest Group is currently partnering with EMBL’s Microscopy Optics and Image Analysis interest group (MOIA) in a monthly seminar series. The series is open to members of both institutions and the presentations will be available to the public afterwards.