nanoHUB-U Nanobiosensors L3.11: Sensitivity - Cantilever-based Sensors - Static Response

Table of Contents:
00:09 Lecture 3.11:Cantilever Sensors - Static Response
01:07 Outline
01:54 Reversal of frequency at nanoscale
03:30 Broadening of frequency response
04:38 Frequency change due to damping (in water) in response to Transient Input
06:38 Outline
07:23 Static deflection can be measured
08:24 Static detection: At your supermarket
10:03 An Example: Mass-induced deflection
12:29 Static vs. dynamic response
13:54 Displacement with an static force
16:21 Spring-softening
19:59 Pull-in instability
23:40 Energy Landscape of Spring weakening
24:54 Conclusions

This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.