A Multi-omic single cell and spatial atlas of breast cancer reveals stromal suppression

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Presented By: Alex Swarbrick, PhD

Speaker Biography: Alex graduated with a Bsc (Hons I) in Molecular and Cellular Biology from UNSW in 1995. After obtaining his PhD in 2003 he undertook postdoctoral training with Nobel laureate J. Michael Bishop at the University of California, San Francisco, supported by a CJ Martin Travelling Fellowship from the NHMRC.

Webinar: A Multi-omic Single Cell and Spatial Atlas of Breast Cancer Reveals Stromal Suppression of Anti-Cancer Immunity

Webinar Abstract: We applied CITE-Seq to measure 150 cell surface immune markers and checkpoint proteins simultaneous to RNA-Sequencing. We resolve the tumour-immune milieu with high precision and reveal subsets of CD8 T cells that are specific to luminal and triple-negative breast cancers, with unique checkpoint molecule expression.
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