Revolution in Nucleotide Triphosphate Delivery Across Cell Membranes

Modified nucleoside and nucleotide analogues are compounds designed to mimic their native physiological counterparts. However, these charged compounds are not allowed to pass across the cell membrane.

Tomáš Kraus, Zbigniew Zawada and their colleagues from #IOCBPrague have developed novel nucleoside triphosphate (NTP) transporter that is capable of translocating modified NTP across the cell membrane in the form of a transporter-NTP complex. And this is how it works…