Muscle Hypertrophy vs. Hyperplasia | How Muscle Grows

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Muscle Hypertrophy vs. Hyperplasia:

Myofibrils/ satellite cells are activated by a hormonal cascade

Testosterone causes GH release and helps convert IGF-1 to MGF

IGF-1 turns into mechano growth factor MGF and increases Protein synthesis

Higher Volume Training is typically optimal for testosterone response

Steps: Stimulus, signal, gene expression, protein synthesis

Tendon growth:

Hormone response can increase collage deposition
Extracellular matrix expands and reforms
Increased tissue tolerance
You can do more plyometrics
You can run longer, faster, jump higher without getting hurt

Credit to Dr. Andy Galpin, Greg Knuckles, Mike Zourdos, Brad Schoenfeld, and the team at MASS research review for posting information on various platforms that helped me make this video.

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Disclaimer: This video does not have any affiliation with, or any recognition, sponsorship, or endorsement by, the NSCA. CSCS® and Certified Strength and Conditioning Specialist® are registered trademarks of the National Strength and Conditioning Association.

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Just WOW! I am studying right now for Personal Trainer and Nutrition and you cannot make it better. Thank you so much for the information!

danielasthory
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Reading the book for the NSCA CSCS and came across a mention of hyperplasia vs. hypertrophy but wanted to understand it better. Had heard of hyperplasia in regards to abnormal growth of cells in certain medical conditions but wasn't familiar with it in regards to muscular growth. Was happy to see you had a video on it as I've found your content to be very helpful in my studies thus far. Thanks!

cameronthibault
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There's some facts (constituing the system) I want to share

1. There is a supercompensation principle (physiological proccess).
2. There are energy system supercompensation (simplistically) and muscle supercompensation (satellites's repair process)
3. To achieve results we have to train during the superc.'s peak period.
4. Superc. proccess is preceded by recovery period.
5. Energy system's recovery end in few days and superc. reaches it peak at third day after las training.
6. Muscle recovery lasts for 9-12 days and it's superc reaches it peak at 13-15th day after last training. (so we have to have a training that could provoke a stress response on 13-15 day)
7. If we want to grow our muscles we have to train hard enough (100% tension) to provoke a stress response. A 100% intensive training should be done no more often than once per 14 days.
8. But during these 2 weeks we should work with rising tension. 6 trainings per 2 week should be like: 50-60-70-80-90-100% (tensive measures by weight value)
9. These 2 weeks called microcycle.
10. There are 3 mycrocycles + 2weeks of rest (8 week total for a mAcrocycle)
11. At every workout we perform only 1 working approach (with several warm-up approaches before it with minimal weight 10-20%)
12. In the first microcycle we perform 15 reps, in the 2nd 10, in the 3rd 10.

ДжонБэйлтон
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Younger people have muscle that is more sensitive to protein intake yet need a "bolus" of maybe 30 grams in the meal. Older people need more, perhaps 50 grams of protein so the muscle "sees" it. Having enough at one shot helps stimulate muscle build. Getting at least 50 grams three times a day should be pretty easy and helpful.

anzaborrego
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I would like to hear more about the hyperplasia process and hyperplasia training methodology

ПавелСухоруков-бю
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Heard you are moving across the country after school because of a job offer. Congrats man

SquatSimp
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Thank you for exactly what i was looking for

cHAOs
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Thank you so much for these information

lorianelder
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excellent explanation.. I really understood this so well.. A big thank you!! 😃 🙏🏽

ajaynangalia
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Are hypertrophy muscles stronger than larger hyperplasia muscles for example? Are those huge Belgian blue cows caused by Myostatin deficiency actually stronger than normal cows?

jastheavatar
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interesting but would like to understand more about the function and type of training for each type of muscle growth and the peculiarities of function in each type?. ( not everyone wants to be a bodybuilder) . Perhaps some examples of the sports that each type of muscle can help most? Tnks

ashzavalajaidar
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hey i love the video, i have a question. in terms of muscle growth lets say for an average joe where to workout and not consume enough protein. how does the fibers truly heal, and why does he gain muscle if the fibers are not truly healed. because as you said it is optimal for one to be intaking protein consistently every day because of the IGF1 phase, so if one was not taking protein or the proper amount, how is the process of their muscle growth, does their muscles stay the same? does the fibers dont heal, or does it heal on its own because of its protein reserves and if that is true does it heal back to just when it tore or does it over compensate but only by a little efficiency due to lack of protein intake.

if you would answer this, it be so greatly appreciated

awolopeimperium
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is it true that hyperplasia cant occur with the 3 tissue types(Cardiac muscle, Skeletal Muslce, and Nerves) because they do not have reverse stem cells so new cells cannot be made? and if that is true then where does hyperplasia occur and how does it contribute to hypertrophy

juansamudio
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Coming from tom platz' interview with golden era bookworm. Good watch

juggernogsoda
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Would taking collagen peptides help?

Underrated channel btw 😊

blueraptor
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Trying to do a really long water fast and shed evening, fat and muscle to kind of start a new.

Anyone have any fairly scientific visited or take scientific articles on museums hypo trophy, catabolism, and muscle degradation?

johnathanabrams
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Thank you for the video! Great info, I'm interested to know how does this process relate to the principle that is preached quite a lot of full body training every day or 5/7 days a week. They say that muscle synthesis peaks for the 24-48 hours or so after training therefore this every day full body method has been getting popular, but you are saying that this process actually takes up to 72 hours, of course this value is varied depending on the extent of the damage done I suppose. What is your take on the optimization of training frequency for maximum muscle growth in regards to this information? Also let's say I did a hard leg day and felt sore for 5 days+, is this an indication that muscle synthesis is happening for over 5 days long?

hornet-hv
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Another fantastic video, thanks soo much 🙌🏽 at 4:40 in relation to consuming protein in a spaced out manner of 48-72hrs post session, (instead of stressing to get protein in just after the session itself) is this info in the CSCS book? I would love to reference it, thanks so much!

sineadwhite
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I really loved your video, altho what is hyperplasia?

hoshangchakravarty
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mechanical tension is only true driver of hypertrophy

mikeeerobbb