Pons Lesions

18:00 In Raymond Syndrome, the CN VI and Corticospinal fibers are affected, in some cases the Facial nerve is affected as well
30:51 in Locked-in Syndrome, the loss of horizontal gaze is caused primarily due to the Paramedial Pontine Reticular Formation (PPRF) lesion , CN VI and IV can sometimes be affected

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[nandaninagarathne]

Today only I came accross this.
Very clearly explained.

Iam a victim of pontine Stroke .
Recovered from most of the signs and symptoms of Locked In Syndrome. But still have a walking disability.

Today I clearly understood what happened to me.

Excellent.

Thank u very much.

[francescaitta]

Love your teaching method. This ONLY way to learn the syndromes is to understand them. Thank you for your work

[himanshuambilkar]

Pons lesion-
Ventropontine syndrome-
Ipsilateral facial nerve palsy.
Ipsilateral lateral rectus plasy.
Contralateral hemiplegia.
Foville syndrome-
Ipsilateral facial nerve palsy.
Ipsilateral lateral rectus palsy.
Contralateral hemiplegia.
Ipsilateral gaze palsy due to paramedian pontine nuclear reticular formation.
Artery invovled-
Paramedian branch of basilar artery.
Short circumferential and long branches of basilar artery.
Anterior inferior cerebellar artery.

Lateral pontine syndrome-
Marie foix syndrome-
Contralateral hemiplegia
Contralateral loss of crude touch pain temperature.
Ipsilateral ataxia cerebellar
Deafness.

Locked in syndrome-
Quadriplegia
Horizontal gaze palsy.
Bilateral internuclear opthalmoplegia.
Reticular formation is intact.

Pons lesion-
Vental pontine
Foville syndrome
Lateral pontine
Locked in

Thank you sir

[chesslord]

Hey there Zach, amazing content as usual. Would like to point out a correction.
At 18:01 while discussing Raymond Sx, you describe it as Ipsilateral facial nerve palsy + Contralateral hemiplegia. However, afaik, it is Ipsilateral 6th nerve (abducens) palsy + c/l hemiplegia.
Also, some authors have suggested two presentations of raymond Sx (with & without facial paresis). But all agree on the involvement of Abducens nerve.
Hope you have a look at this. Thanks for the great video.

[maner.fatima]

You’re looking great Zach!!!
Ninja Nerd lectures are the best!!
Love ya guys! 💙💙

[BIOLAOSIFESO]

Great presentation Zach(and team)👍
I would like to add-
In Marie Foix syndrome, one could also have ipsilateral facial nerve palsy, Horner's syndrome, nystagmus and vomitting.
Locked in syndrome has 2 other presentations apart from the classical presentation you described.
There's the incomplete immobility variant in which there is some preservation of motor function and
There's the complete immobility variant where in addition, there's also loss of vertical eye movement BUT preservation of cortical function demonstrated on EEG.

[josetrujillo]

“Where the heck is that blue marker?”- lol! Thanks for teaching us Zach! Thank you Ninja Nerds!

[LittleGenius]

Searching entire YouTube n got from the man i view frequently ☺️.
The best

[vatsalgarg]

CORRECTION: Raymond's syndrome has ipsilateral abducent nerve palsy, not facial nerve - checked various sources

[jeremiahgounder]

Did you know that one cannot breathe while smiling





Now I just made a person smile for no reason

[Sunflower-vpbc]

specifically enjoyed ur explanation of locked in syndrome---what a masterpiece

[clivewurr]

Thank you Prof Murphy. Coolest Professor every.

[gritajophy]

Loved the brainstem videos...It's gud to c u back teaching...
Really looking forward to ur future videos :D...
Plz keep teaching neurology🤩🤩....U really make it much more simplified😄

[nayanranjanbharadwaj]

If i say u r intelligent it is not enough a lot of people r intelligent u r a born teacher u know how to teach what is first second third like so to be taught after having your lecture on the subject need not to open book your personality your voice your features all are beautiful your knowledge your delivery marvellous your qualities r beyond words your musical delivery just like a soothing song i m senior citizen of City Agra a homoeopathic physician u have made me new i have nothing to pay only wishes i wish u a healthy long prosperous life to u and to your family

[ArYaNkHaN-Hi]

I saw ur many lectures it's so helpful& as well as so easy to understand it & one thing more look fit😊😍😍

[lukesmith]

Everybody's asking where is the lesion, but no-one is asking how is the lesion 😢

[zezozezotheworldisnotmadeo]

First time ever understand it...big respect 🙇‍♀️

[denadalala]

Thanks a lot. You are saving my life 😊❤️

[arbazahmed]

You made lectures like a piece of cake 😎

[mudassirbilal]

Really helpful 👍
Lots of love and respect from Pakistan 🥰