Derm Residents: Nail unit squamous cell carcinoma

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* Nail unit squamous cell carcinoma (SCC) is difficult to diagnose or suspect clinically because of its tendency to present as nonspecific nail plate changes. The tumors usually are painless and asymptomatic, leading to a delay in diagnosis. In this resident takeover, Daniel R. Mazori, MD, talks to Mohammed Dany, MD, PhD, about nail unit SCC and the importance of early diagnosis to avoid local destruction and bone invasion. “Usually, any subungual lesion in an immunosuppressed individual, especially if it is chronic and nonhealing, would prompt a biopsy,” Dr. Dany explains. They also discuss other risk factors and potential causes for nail unit SCC, with a particular focus on human papillomavirus infection, as well as treatment options including surgery. Article:

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* Hosts: Nick Andrews; Daniel R. Mazori, MD (State University of New York, Brooklyn) Guests: Mohammed Dany, MD, PhD (Department of Dermatology, University of Pennsylvania, Philadelphia) Disclosures: Dr. Mazori and Dr. Dany report no conflict of interest. Show notes by: Allegra Sparta, Melissa Sears *

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