Spray Dried Biologics: Formulation and Process Considerations

Spray drying is a precedented method for the continuous manufacturing of engineered dry powder particles from a liquid feed solution. The process is readily tunable and scalable which allows for rapid formulation screening, using a small amount of active, while also directly translatable to cGMP manufacture. Given these attributes the technology is applicable to formulating and processing biotherapeutic products.

Key Learning Objectives:

Show why spray drying is applicable and enabling for biologics
Understand spray drying formulation considerations
How to tune the spray drying process to biologics
Delivery options for spray dried biologics

Presented by:
Michael Burke, Sr. Scientist, Product Development, Capsugel