e-Seminar Series on Translational Biomedical Engineering with Prof. Sean Wu (2021-10-20)

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Prof. Wu's research career has been dedicated to making fundamental discoveries in developmental and regenerative biology of the cardiovascular system and applies these findings to prevent and treat the damaged heart. He has made major contributions in the isolation and characterization of cardiac progenitor cells and their differentiated progenies from mouse embryos and human iPSCs. He has considerable expertise in human iPSC modeling of cardiovascular diseases using genome editing technologies and tissue engineering approaches. His recent work focused on single-cell transcriptomics of the developing cardiac conduction system and bioinformatic annotation of single-cell RNA sequencing data. His work has been funded by the NIH Director’s New Innovator Award, NIH Director’s Pioneer Award, the California Institute of Regenerative Medicine, the NHLBI Progenitor CellBiology Consortium, and is currently supported by the NIGMS RM1Multidisciplinary Collaborative Grant, multiple collaborative NIH R01 grants, and the Established Investigator Award from American Heart Assoc., among others.

He has published in peer-reviewed journals such as Nature, Science, Circulation, Developmental Cell, and Cell Stem Cell, among others.

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