Synthetic Biology and Stability Analysis in the Toggle Switch

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MIT 8.591J Systems Biology, Fall 2014
Instructor: Jeff Gore

In this lecture, Prof. Jeff Gore discusses the toggle switch, or two genes that repress each other. He then moves on to dimensionless equations and stability analysis.

License: Creative Commons BY-NC-SA
  1. MIT OpenCourseWare
  2. systems biology
  3. biology
  4. physics
  5. proteins
  6. gene expression
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Комментарии
Автор

It is admirable how prof. Gore focuses on the intuitive understanding, as opposed to mere rigor, derivations and proofs. Excellent teacher!

maartendj
Автор

Excellent video! I've been looking for a clear explenation, thanks!

osielrecoder
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Fill high #simulators  <simulator> Dig deep <simulators> #simulator  . refference to previous lecture notes.

GuillermoRobles
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How can i find all videos of molecular biology I didn't get it plz someone suggest me... I want to learn from starting

shalaka
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Does anyone know if this is an undergraduate course?

SofiasBio
Автор

The last calculation is not quite right because the system is stable at a point where x is negative which is impossible for a biological system. So there will be only one possible configuration for biological system which is a exactly the opposite of the one on the board.

lihe