The Buried Study showing Saturated Fat is Healthy [Study 228, 229]

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References
[1] Ramsden C E, Zamora D, Majchrzak-Hong S, Faurot K R, Broste S K, Frantz R P et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73) BMJ 2016; 353 :i1246 doi:10.1136/bmj.i1246

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[Physionic]

I'll go ahead and say this now so I can avoid answering the same question over and over: This is a look at the Minnesota Coronary Experiment, not the 7 Countries Study. I haven't looked at the 7 Countries Study. This is an analysis of this study and the conclusions do not extend beyond this study. If you still feel Dr. Keys is a liar and a fraud, that's fine - I'm only here to point out some major issues with this singular, influential study so you can hear something other than the one sided explanations offered by some popular contrarians. Thanks for watching.

[craig]

I find it strange how humans have existed for who knows how long and yet still cant figure out what they should and shouldn't be eating.

[NutritionMadeSimple]

Great sleuthing. the design of the trial was ground-breaking (massive scale, and inpatients meant full dietary control). tragically, the results became a monumental mess due to both the attrition you mentioned (nation wide policies changed and patients were discharged) and the trans fats issue the authors couldn't have anticipated without a crystal ball :) 

follow up was projected to exceed 3 years but averaged 13months in the end...

many subjects also stayed at the hospital temporarily, sometimes leaving and coming back later, making results uninterpretable

at the end of the day science hinges on reproducibility. 15 trials have addressed this question of saturated fats and CVD, and the full picture tells a very different story from just Minnesota & Sydney in a vacuum :)

[donquihote]

When industry experiments to find uses for every resource, it is not far fetched to consider the possibility of a paid outcome. Byproducts become products and require a Market. If it can be built, chemically induced or grown, it is a value to Business, Economy, and people. Seed oils have been used for fuel, lubrication, etc... for a long time. To create a Market in the Human Diet is incredibly lucrative. Suddenly, a byproduct of Cotton production becomes a money maker. It is correct to be skeptical about anyones studies. Everyone has a price.

[freesk]

If you can get up out of your hospital bed to go to the smoking area, you probably have a better prognosis. And the very elderly tend to thin out before they die. Having a higher BMI is associated with better outcomes.

[davycrockett]

Thank you for being scientifically honest!

[CriticalLinker]

As soon as you described the study design, red flags were waving all over the place for me. Control what 10, 000 mental hospital patients eat? Sure. What could be easier? Having worked in such hospitals during that time period, i can say without a doubt that the hospitals generally provided poor-quality, poorly cooked meals which patients supplemented by buying supplies at local shops. Most patients were not locked in so they could easily acquire food from other sources. They often went home on 'leave', and visitors brought them chocolates. Oh - and almost all of them smoked like chimneys.

[CatholicSatan]

I recall that series of dumb questions by lawyers when one young lawyer asked the doctor on the stand if the victim was deceased at the time of the autopsy. The doctor replied, "Well he certainly was by the time I'd finished with him."

[DaxYou]

Bankers do this to me ALL the time too. I DON'T SPEAK 'BANKER". All I hear in this is FAT and all I know is every Chef on this planet defines that as FLAVOUR! Poly-fat, Low-fat, High-fat, tri-fat, non-fat, saturated-fat, unsaturated-fat, non-unsaturated-fat, vaseline, and how many others are there? WTF....just tell me to eat butter and olive oil. DONE! As of now, I have NO clue up or down, side to side, front to back. I am sick and tired of having to read the ingredients on labels, it should it's good for you, it's in if not take it out! Any company putting bad stuff in food, put the CEO in jail TODAY!

[tacitus]

Good explanations - heard whispers about this study for awhile. One observation - to the best of my knowledge no one was analyzing trans fat issues until 30 years after this study and Harvard guys doing epidemiology noticed it.

[RichardFeinman-yflx]

Before discovery of the buried data, the study was often cited (by AHA for example) as supporting risk of saturated fat. Critics pointed out some of the issues (attrition, for example). And the many failures to show risk are well-known. In this business, you have to assume that research is honest unless you find examples like this. One of the researchers admitted that they buried the data because it was “disappointing.” The real question you are raising is why they didn’t bury the whole study. Nutritional epidemiology, in any case, has given us virtually no testable information.

[zhilahaghbin]

Thanks much Nick, , amazing as usual, how deep you dive into the subject and clarify issues. Thanks for your hard work.

[pommieMJ]

A good and detailed analysis of this study/experiment. Thanks for posting this, got me thinking which I am always a big fan of. Thanks again

[mj]

This is the best video on this topic I have ever seen. Thank you for publishing it!

[ytuser]

Time to fix my over 20 yrs of not smoking.

[golaoi]

There's an interesting point that maybe you don't know, but you will now. AFAIK the male patients who lived longest in Framingham were 25% heavier than their "ideal" weight.

[ArchaeanDragon]

Too bad Keys didn't "bury" his shoddy 7 countries study. That one was definitely a pile of rubbish. Instead, he touted it for years and used it to browbeat everyone else's research, including Yudkin's.

Keys was the worst. :(

[cmburns]

But here’s a question for you. If the results had in fact supported their “saturated fat -> higher mortality” hypothesis, then do you think they would’ve published the results? I think they would have

[Marlen-CruzCommercial_]

Common sense always told me that the good old EGGS in the morning, steak in the afternoon was healthy.

[mariomenezes]

Excellent analysis! Thank you! Watching content like this allows me to get away from the conspiracy mindset and realize that context matters. What is not said is as important as what is said. If the doctors had only published the reasons for discarding the study, life would have been simple. They did not realize the controversy that may be caused by not explaining. They may also not have realized that so many non medical people would know so much about health due to data availability on the internet. Thank you!