Somite Formation & 90min clock

Discussion of how somites form in chick embryos and how the 90min clock works in relation to negative feedback loops.

**Typo in video** I've reversed A + B accidentally on the ABC flower model diagram. B should be on top and A on the left. However the principle of combinatorial gene expression still applies! Check out out ABC flower model below for a more in depth explanation.

Music: Cipher (Electronic Light) by Kevin Macleod

[susanhill]

There are so few videos on this. Thank you for explaining this in very understandable terms for this grad student

[bluenoserabbit]

Insanely helpful video! So informative but easy to follow, I've been reading for days only to understand it better in minutes thanks to you!

[alimahdighazal]

I love you for this well-scripted video !!!! i understood everything

[irisattas]

Thank you for this great video. Your explanation was very clear

[Turret]

Also come Your work is needed, you make great videos ❤️

[procrastinatorTM]

Very good video! You explained it so well and helped me very much in understanding it better! Thank you very much!

[maryspreen]

Very clear, thank you. What are the concentrations of RA and FGF traveling in? Totally extracellular goo? What are the main molecules? Are there experiments showing that anything (like temp) could slow down or speed up the clock? If so is it by affecting the movement of RA and FGF, or the cycle time of the neg feedback loops?

[CarlosRosales-uq]

How does somite formation occur in organisms such as snakes?

[jameshammond]

Do you have a reference for the gene regulatory network shown at ~2:11?

[Turret]

If possible could you give the answer to review question 2? I believe it has to do with pre-determined cells but I am not quit sure how the orientation effects the development ...

[LuuhTMJ]

Nice video! From which book did you get most of the images from?